引用本文:黄菊清.妊娠期药物不良反应126例分析[J].中国临床新医学,2017,10(6):571-573.
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妊娠期药物不良反应126例分析
黄菊清
546100 广西,来宾市人民医院药剂科
摘要:
[摘要] 目的 分析妊娠期药物致不良反应126例的一般规律及特点,从而减少或避免药物不良反应(ADR)发生,促进临床合理用药。方法 对来宾市不良反应监测中心2012~2015年间收集到的桂中地区妊娠期ADR报告进行汇总分析。结果 126例ADR报告中,妊娠期≥28周的发生率最高,共90例,占71.43%;作用子宫药物类38例居首位,占30.16%,其次为抗菌药物36例,占28.57%。在ADR涉及的孕妇安全用药级别中,B级药物最多,占60%。ADR涉及的主要临床表现为寒战和皮疹。结论 了解妊娠期ADR的特点、注意事项,严格遵守操作规程,避免ADR的发生。
关键词:  药物不良反应  妊娠期药物  合理用药
DOI:10.3969/j.issn.1674-3806.2017.06.23
分类号:R 96
基金项目:
Adverse drug reactions during pregnancy:a report of 126 cases
HUANG Ju-qing
Department of Pharmacy, the People′s Hospital of Laibin City, Guangxi 546100, China
Abstract:
[Abstract] Objective To explore the general characteristics and regularity of the adverse drug reactions(ADRs) during pregnancy and to reduce or avoid ADRs, and further promote the clinical rational use of drugs.Methods The reports of ADRs during pregnancy were collected by the adverse reaction monitoring center of Laibin from 2012 to 2015 in Guizhong region.Results Of a total of 126 cases with ADRs, 90 cases were pregnant more than 27 weeks showing the highest proportion(71.43%); 38 cases were involved in uterus drugs accounting for 30.16%, followed by antibacterial drugs(36 cases), accounting for 28.57%. The class B drugs were the most common drugs that involved ADRs(60%). The main clinical manifestations of ADR were chills and skin rashes.Conclusion Understanding of the characteristics of adverse drug reactions and notes in pregnancy and strictly following the operating rules in the operation process help to avoid the occurrence of adverse drug reactions.
Key words:  Adverse drug reactions(ADRs)  Medication during pregnancy  Rational use of drugs