| 摘要: |
| ［摘要］ 目的 探讨轻度支气管哮喘采用痰热清注射液雾化治疗的临床效果。方法 选择2015-06～2016-06收治的支气管哮喘患者60例，根据治疗方案的不同分为两组。对照组30例实施常规抗感染、糖皮质激素、氨茶碱及吸氧对症治疗。观察组30例在对照组治疗的基础上加用痰热清注射液雾化吸入治疗。两组均治疗4周。观察两组患者治疗前后血清内皮素(ET)、一氧化氮(NO)水平及临床疗效情况。结果 两组患者治疗后，病情均有所改善。观察组显效18例，有效10例，无效2例，对照组显效11例，有效11例，无效8例，观察组疗效优于对照组(P<0.05)。治疗前两组患者血清ET、NO水平相比较差异无统计学意义(P>0.05)。治疗后观察组的血清ET、NO水平下降幅度明显优于对照组，差异具有统计学意义(P<0.05)。结论 痰热清注射液雾化吸入治疗轻度支气管哮喘，有效改善了患者血清ET和NO的水平，缓解临床症状，提高治疗效果，减少不良反应，值得推广应用。 |
| 关键词: 支气管哮喘 血清ET 一氧化氮 痰热清注射液 临床效果 |
| DOI：10.3969/j.issn.1674-3806.2017.08.06 |
| 分类号:R 562.2+5 |
| 基金项目:广西卫计委科研课题（编号:Z2014268） |
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| Study on the treatment of mild bronchial asthma by aerosol inhalation of Tanreqing injection |
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MENG Jian-feng
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Study on the treatment of mild bronchial asthma by aerosol inhalation of Tanreqing injection
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| Abstract: |
| ［Abstract］ Objective To investigate the clinical effect of aerosol inhalation of Tanreqing injection on the patients with mild bronchial asthma.Methods 60 patients with mild bronchial asthma admitted to our hospital from June 2015 to June 2016 were selected and were divided into three groups according to the different treatment regimens. The control group(n=30) received conventional expectant treatments of anti-infection, glucocorticoid, aminophylline and oxygen inhalation. The observation group(n=30) received the same treatment as the control group plus aerosol inhalation of Tanreqing injection. Both of the two groups were treated for 4 weeks and the levels of endothelin(ET) and nitric oxide(No), and the clinical efficacy were observed.Results After the treatment, the conditions of the patients were improved in both of the two groups. 18 cases were makkedly effective, 10 cases effective and 2 cases ineffective in the control group, while 11 cases were markedly effective, 11 cases effective, and 8 cases ineffective in the control group，with a better clinical effect in the observation group(P<0.05). There were no significant differences in the levels of ET and NO between the two groups before the treatment. After the treatment, the levels of serum ET and NO decreased more significantly in the observation group than those in the control group. The disappearance time of cough, dyspnea and wheezing in the observation group was significantly shorter than that in the control group(P<0.05).Conclusion Aerosol inhalation of Tanreqing injection can effectively improve the levels of serum ET and NO, relieve the clinical symptoms, and improve the therapeutic effect in the patients with mild bronchial asthma. |
| Key words: Bronchial asthma Serum endothelin(ET) Nitric oxide Tanreqing injection Clinical effect |
