引用本文:樊同莲,夏燕华.孟鲁司特钠结合阿奇霉素治疗小儿支原体肺炎的临床疗效观察[J].中国临床新医学,2017,10(8):772-775.
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孟鲁司特钠结合阿奇霉素治疗小儿支原体肺炎的临床疗效观察
樊同莲,夏燕华
526020 广东,肇庆市中医院儿科(樊同莲),呼吸科(夏燕华)
摘要:
[摘要] 目的 探讨孟鲁司特钠结合阿奇霉素治疗小儿支原体肺炎的疗效。方法 选取该院2014-01~2016-08治疗的小儿支原体肺炎患儿46例,随机分为研究组及对照组,各23例。对照组采用单纯阿奇霉素治疗,研究组在对照组的基础上联合孟鲁司特钠治疗。均维持用药2~3个疗程,根据症状体征改善情况及实验室指标等方面评估用药效果。结果 研究组治愈6例,显效11例,有效5例,无效1例。对照组治愈3例,显效7例,有效7例,无效6例。研究组疗效优于对照组(P<0.05)。研究组临床症状、体征消失时间及平均住院时间明显短于对照组(P<0.05)。两组患儿治疗前C反应蛋白(CRP)水平差异无统计学意义,而治疗后两组CRP水平均降低明显(P<0.05)。研究组并发症发生率为8.70%,明显低于对照组的34.78%(P<0.05)。结论 孟鲁司特钠结合阿奇霉素治疗小儿支原体肺炎可提高疗效,有效改善症状和体征,并发症轻微,预后良好,值得临床推广。
关键词:  孟鲁司特钠  阿奇霉素  小儿支原体肺炎  临床疗效
DOI:10.3969/j.issn.1674-3806.2017.08.17
分类号:R 725.6
基金项目:
Clinical curative effect of montelukast sodium combined with azithromycin on the treatment of mycoplasma pneumonia in children
FAN Tong-lian, XIA Yan-hua
Clinical curative effect of montelukast sodium combined with azithromycin on the treatment of mycoplasma pneumonia in children
Abstract:
[Abstract] Objective To explore the clinical curative effect of montelukast sodium combined with azithromycin on the treatment of mycoplasma pneumonia in children.Methods 46 children with mycoplasma pneumonia were randomly divided into the research group and the control group, the control group received azithromycin treatment alone, and the research group was treated with montelukast sodium plus azithromycin. Both of the two groups maintained 2~3 course of treatment. The drug effects were evaluated according to the symptom signs and laboratory indexes.Results In the research group, 6 cases were cured, 11 cases markedly improved, 5 cases effective and 1 case ineffective. In the control group, 3 cases were cured, 7 cases markedly improved, 7 cases effective and 6 cases ineffective. The clinical effect of the research group was better than that of the control group(P<0.05). The disappearance time of clinical symptoms and signs in the research group was significantly shorter than that in the control group. The average hospital stay was significantly shorter in the research group than that in the control group. There was no significant difference in C-reactive protein(CRP) between the two groups before the treatment. The levels of CRP after the treatment were significantly lower than those before the treatment in both of the two groups(P<0.05). The complication rate of the research group was significantly lower than that of the control group(8.70% vs 34.78%)(P<0.05).Conclusion Montelukast sodium combined with azithromycin therapy can improve the curative effect for the children with mycoplasma pneumonia.
Key words:  Montelukast sodium  Azithromycin  Mycoplasma pneumonia in children  Clinical effect