| 摘要: |
| ［摘要］ 目的 探讨重症医学科（ICU）内复杂腹腔感染患者的病原菌特征。方法 回顾性分析2013-01～2016-12岑溪市人民医院ICU收治的82例确诊为复杂腹腔感染且有腹腔病原学资料的临床资料，分析腹腔细菌学分布情况。结果 （1）复杂腹腔感染病原菌的分布：革兰氏阴性菌52.7%（58/110），真菌29.1%（32/110），革兰氏阳性菌18.2%（20/110）；（2）医院获得性感染组发生真菌感染的比例高于社区获得性感染组（P<0.05）；（3）放弃/死亡组较存活组更容易发生真菌感染与混合细菌感染（P<0.05），同时不恰当使用抗菌药物的比例更高（P<0.05）。结论 复杂腹腔感染病原菌以革兰氏阴性菌和真菌发生率较高；腹部手术后腹腔真菌（主要是白色念珠菌）以及混合感染发生率较高，且影响预后，值得临床重视。 |
| 关键词: 腹腔感染 病原菌 重症医学科 |
| DOI：10.3969/j.issn.1674-3806.2017.09.04 |
| 分类号:R 656；R 378 |
| 基金项目:广西科学研究与技术开发计划项目（编号：桂科攻14124003-8） |
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| Analysis of pathogens of complicated intra-abdominal infections in Intensive Care Unit |
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LIU Yuan-bo, ZHANG Hong-bin, ZENG Ming-hao, et al.
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Intensive Care Unit, the People′s Hospital of Cenxi City, Guangxi 543200, China
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| Abstract: |
| ［Abstract］ Objective To investigate the characteristics of pathogens in patients with complicated intra-abdominal infections in Intensive Care Unit(ICU).Methods The clinical data of 82 ICU patients with complicated intra-abdominal infections were retrospectively analyzed and the distribution of pathogenic bacteria was described.Results (1) Gram-negative bacteria were found in 58 cases(52.7%), fungi in 32 cases(29.1%) and Gram-positive bacteria in 20 cases(18.2%).(2)The proportion of fungal infections was higher in the hospital-acquired group than that in the community-acquired group（P<0.05）.（3）Compared with the survival group, the death group had higher fungal infections and bactera mixed infections（P<0.05）, and more cases of initial inappropriate antibiotic therapy(P<0.05).Conclusion The two most frequently isolated pathogens in the patients with complicated intra-abdominal infections are Gram-negative bacteria and fungi. Laparotomy is a risk factor for the incidence of complications such as fungal infections(mostly result from Candia albicans) and mixed infections, which affects the prognosis. |
| Key words: Intra-abdominal infections Pathogenic bacteria Intensive Care Unit(ICU) |
