| 摘要: |
| ［摘要］ 目的 探讨孟鲁司特钠联合舒利迭治疗支气管哮喘的效果。方法 选取2015-01～2016-06该院收治的72例支气管哮喘患者，随机分为两组，每组36例。对照组给予舒利迭100 μg/d，2次/d。联合组给予舒利迭外，孟鲁司特钠10 mg/次，1次/d。均治疗12周。结果 联合组显效23例，好转11例，无效2例。对照组显效14例，好转13例，无效9例。联合组临床疗效明显优于对照组（P<0.05）。治疗前，两组患者的第一秒用力吸气容积（FEV1）、呼气峰值流速（PEF）与用力肺活量（FVC）比较差异无统计学意义（P>0.05）；治疗后，两组患者的各项肺功能指标均得到显著改善，且联合组患者的肺功能指标显著高于对照组（P<0.05）。结论 孟鲁司特钠联合舒利迭治疗支气管哮喘，可以明显改善患者的肺功能和临床症状，治疗效果显著。 |
| 关键词: 孟鲁司特钠 舒利迭 支气管哮喘 |
| DOI：10.3969/j.issn.1674-3806.2017.10.09 |
| 分类号:R 56 |
| 基金项目: |
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| The clinical effect of montelukast sodium combined with seretide on bronchial asthma |
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HOU Hui-na
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Department of Respiratory Medicine, the Third People′s Hospital of Shangqiu City, Henan 476000, China
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| Abstract: |
| ［Abstract］ Objective To explore the clinical effect of montelukast sodium combined with seretide on bronchial asthma.Methods 72 patients with bronchial asthma were selected in our hospital from January 2015 to June 2016 and were randomly divided into two groups, with 36 cases in each group. The control group received seretide(50 μg, bid), and the treatment group received montelukast sodium(10 mg, qd) combined with seretide(50 μg, bid) for 12 weeks. The clinical efficacy was compared between the two groups.Results In the treatment group, 23 cases were markedly effective, 11 cases effective, and 2 cases invalid. In the control group, 14 cases were markedly effective, 13 cases effective, 9 cases invalid. The curative effect of the treatment group was significantly better than that of the control group(P<0.05). Before the treatment, there were no significant differences in forced expiratory volume in one second(FEV1), peak expiratory flow(PEF) and forced vital capacity(FVC) between the two groups(P>0.05); After the treatment, the pulmonary function was significantly higher than that before the treatment in both of the two groups, and the pulmonary function of the treatment group was significantly higher than that of the control group after the treatment(P<0.05).Conclusion Montelukast sodium combined with seretide can significantly improve the lung function and clinical symptoms in the patients with bronchial asthma. |
| Key words: Montelukast sodium Seretide Bronchial asthma |
