| 摘要: |
| ［摘要］ 目的 研究前哨淋巴结活检术对早期乳腺癌患者术后免疫功能及预后的影响。方法 选择该院2015-02～2016-07收治的早期乳腺癌患者90例，按治疗方式不同分为观察组和对照组各45例。观察组实施前哨淋巴结活检术，对照组实施腋窝淋巴结清扫术。比较两组患者术后免疫功能和肩关节功能。结果 术前两组患者的CD8+、CD4+相比，差异无统计学意义（P>0.05）；术后观察组CD4+较对照组有明显提高，而CD8+低于对照组，差异有统计学意义（P<0.05）；观察组肩关节功能明显优于对照组，差异有统计学意义（P<0.05）。结论 对早期乳腺癌患者实施前哨淋巴结活检术能有效改善患者术后免疫功能和肩关节功能。 |
| 关键词: 前哨淋巴结活检术 早期乳腺癌 免疫功能 预后 |
| DOI：10.3969/j.issn.1674-3806.2018.03.15 |
| 分类号:R 737.9 |
| 基金项目: |
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| Effect of sentinel lymph node biopsy on postoperative immune function and prognosis in patients with early breast cancer |
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ZHANG Yu-feng
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Department of Tumor Surgery, General Hospital of Henan Shenhuo Group Employees, Henan 476600, China
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| Abstract: |
| ［Abstract］ Objective To study the effect of sentinel lymph node biopsy on postoperative immune function and prognosis in patients with early breast cancer.Methods 90 patients with early breast cancer in our hospital from February 2015 to July 2016 were selected and divided into two groups according to the different treatment methods, with 45 cases in each group. The patients in the observation group were treated with sentinel lymph node biopsy, and axillary lymph node dissection was performed for the patients in the control group. The postoperative immune function and shoulder function were compared between the two groups.Results There were no significant differences in the levels of CD8+ and CD4+ between the two groups before operation(P>0.05). The level of CD4+ in the observation group was significantly higher than that in the control group, while the level of CD8+ in the observation group was lower than that in the control group(P<0.05). The excellent and good rate of shoulder joint function in the observation group was significantly higher than that in the control group(P<0.05).Conclusion Sentinel lymph node biopsy can effectively improve postoperative immune function and shoulder function for the patients with early breast cancer. |
| Key words: Sentinel lymph node biopsy Early breast cancer Immune function Prognosis |
