| 摘要: |
| ［摘要］ 目的 对比放置曼月乐环和低剂量复方口服避孕药（COC）治疗子宫腺肌病患者疼痛和月经过多的临床效果。方法 62例主诉疼痛和月经过多的子宫腺肌病患者随机分为曼月乐环组和COC组。采用视觉模拟评分法(visual analogue scale,VAS)评估疼痛程度，用月经日记评估月经血量和超声检查估计子宫体积的变化。对比两组患者治疗6个月前后的疼痛程度、月经量和子宫体积的变化情况。结果 两种方法治疗6个月后，疼痛均明显减轻，而且曼月乐环组与COC组相比效果更为明显（P<0.01）；两种治疗方法均显著减少子宫出血量，子宫体积明显缩小，且曼月乐环组比COC组显著（P<0.01）。结论 曼月乐环和COC用于子宫腺肌病的治疗，均能减轻相关疼痛及减少月经出血量，放置曼月乐环比口服COC疗效更好。 |
| 关键词: 子宫腺肌病 复方口服避孕药 曼月乐环 痛经 |
| DOI：10.3969/j.issn.1674-3806.2018.07.02 |
| 分类号:R 71 |
| 基金项目:广西科技攻关计划项目（编号：桂科攻1298003-8-5） |
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| Comparison of levonogestrel-releasing intrauterine system and oral contraceptive for treatment of adenomyosis |
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HUANG Li-dong, WU Yu-ying, CHEN Chang-yi, et al.
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Department of Gynecology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To compare the efficacy of a levonorgestrel-releasing intrauterine system(LNG-IUS) and a low-dose combined oral contraceptive(COC) in reducing adenomyosis-related pain and bleeding. Methods Sixty-two patients with adenomyosis complained of pain and bleeding that were associated with adenomyosis were randomly divided into LNG-IUS group and COC group. The outcomes included the improvement of pain release using a visual analogue scale, menstrual blood loss using a menstrual diary and estimated uterine volume by ultrasound were compared before and 6 months after treatment. Results The adenomyosis-related pain was relieved obviously and the adenomyosis-related bleeding was remarkably reduced and the sizes of uterine were decreased obviously in both of the two groups 6 months after treatment（P<0.01）, however the improvements of the pain release and bleeding in LNG-IUS group were better than those in COC group（P<0.01）. Conclusion Both LNG-IUS and COC can relieve the adenomyosis-related pain and reduce the menstrual bleeding. However, LNG-IUS is more effective than COC for treatment of adenomyosis. |
| Key words: Adenomyosis Combined oral contraceptive（COC） Levonogestrel-releasing intrauterine system Dysmenorrhea |
