| 摘要: |
| ［摘要］ 目的 建立测定甲硝唑原料药中镉含量的测定方法。方法 采用石墨炉原子吸收光谱法，供试品经微波消解处理后测定，镉测定波长228.8 nm,狭缝0.7 nm,光源灯电流8 mA。结果 镉浓度在线性范围0～2 ng/ml范围内与吸光度呈良好线性关系,平均加样回收率为98.4%（RSD=1.2%，n=9）。结论 方法准确快捷，专属性强，检出限低，精密度高，回收率好，线性范围宽，稳定性好。 |
| 关键词: 甲硝唑 石墨炉原子吸收分光光度法 镉 微波消解 |
| DOI：10.3969/j.issn.1674-3806.2019.08.22 |
| 分类号:R 917 |
| 基金项目: |
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| Determination of cadmium in metronidazole by raw materials atomic absorption spectrometry |
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ZHENG Li-wei
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Analysis Room of Tieling Drug Inspection Institute, Liaoning 112000, China
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| Abstract: |
| ［Abstract］ Objective To establish a method for the determination of cadmium in metronidazole raw materials. Methods Graphite furnace atomic absorption spectrometry(GFASS) was used to determine the metronidazole samples after microwave digestion. The cadmium determination wavelength was 228.8 nm, the slit was 0.7 nm, and the light source current was 8 mA. Results There was a good linear relationship between cadmium concentrations and absorbances in the linear range of 0～2 ng/ml, and the average recovery was 98.4%(RSD=1.2%, n=9). Conclusion The method has the advantages of accuracy, quickness,specificity, low detection limit, high precision, good recovery, wide linear range and good stability. |
| Key words: Metronidazole Graphite furnace atomic absorption spectrometry Cadmium Microwave digestion |
