| 摘要: |
| ［摘要］ 目的 对腹腔镜手术和常规开腹手术治疗的子宫肌瘤患者进行回顾性分析，探讨不同手术方式对子宫肌瘤患者机体应激反应及术后并发症发生的影响。方法 选取该院2016-05～2018-06收治的子宫肌瘤患者行腹腔镜手术治疗36例为观察组，行开腹手术治疗36例为对照组。比较两组术前、术后皮质醇（Cor）、去甲肾上腺素（NE）、C-反应蛋白（CRP）、白细胞介素-6（IL-6）、胃泌素和凝血酶原时间（PT）变化情况及手术并发症情况。结果 观察组术后Cor、NE、CRP、IL-6、胃泌素水平和PT明显低于对照组（P<0.05）。观察组术后并发症发生率明显低于对照组，差异有统计学意义（P<0.05）。结论 与常规开腹手术相比，腹腔镜手术能降低子宫肌瘤患者术后应激反应，同时降低术后并发症发生率。 |
| 关键词: 腹腔镜 子宫肌瘤 应激反应 术后并发症 |
| DOI：10.3969/j.issn.1674-3806.2020.07.17 |
| 分类号:R 737.33 |
| 基金项目: |
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| Effects of laparoscopic surgery on stress response and complications in patients with uterine fibroids |
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LIU Yan, YAN Jun-yuan, CHENG Shao-mei, et al.
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Department of Obstetrics and Gynecology, the Third Affiliated Hospital of Shandong First Medical University(Affiliated Hospital of Shandong Academy of Medical Sciences), Jinan 250031, China
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| Abstract: |
| ［Abstract］ Objective To analyze the retrospective study of laparoscopic surgery and conventional laparotomy on the patients with uterine fibroids, and to explore the effects of different operation methods on stress response and postoperative complications of the patients with uterine fibroids. Methods From May 2016 to June 2018, 36 patients with uterine fibroids were selected as the observation group receiving laparoscopic surgery and other 36 uterine fibroid patients as the control group receiving open surgery. The preoperative and postoperative changes of cortisol(Cor), norepinephrine(NE), C-reactive protein(CRP), interleukin-6(IL-6), gastrin and prothrombin time(PT) were compared between the two groups. The operative complications were compared between the two groups. Results The postoperative levels of Cor, NE, CRP, IL-6, gastrin and PT in the observation group were significantly lower than those in the control group(P<0.05), and the incidence of postoperative complications in the observation group was significantly lower than that in the control group, with statistically significant differences between the two groups(P<0.05). Conclusion Compared with conventional open surgery, laparoscopic surgery can reduce the postoperative stress response and the incidence of postoperative complications in the patients with uterine fibroids. |
| Key words: Laparoscope Uterine fibroids Stress response Postoperative complications |
