| 摘要: |
| ［摘要］ 人工耳蜗（CI）自投入使用以来，一直是双耳重度和极重度感音神经性聋患者获得听力的最有效方式。但少部分先天性耳聋患者在CI植入术后，经过听力言语功能训练仍未能获得满意的术后效果。近年来，随着基因检测技术的发展，耳聋基因作为先天性耳聋患者病因学研究取得初步成效，其对CI术后疗效的影响也被广泛研究。该文就耳聋基因突变与CI术后疗效的相关性研究进展进行综述。 |
| 关键词: 耳聋基因 人工耳蜗 术后疗效 |
| DOI：10.3969/j.issn.1674-3806.2021.03.22 |
| 分类号:R 764 |
| 基金项目:广西科技厅重点研发项目（编号：桂科AB17292089）；广西医疗卫生适宜技术开发与推广应用项目（编号：S2017078）；广西卫健委科研课题（编号：Z20170366） |
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| Advances in the study on the correlation between deafness gene mutation and the postoperative efficacy of cochlear implant |
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HUANG Lan-cheng, ZHOU Kai, FENG Meng-long, et al.
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Graduate School, Guangxi Medical University, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Cochlear implant(CI) has been the most effective way to obtain hearing for patients with severe and very severe sensorineural hearing loss since its clinical application. However, a small number of patients with congenital deafness have not achieved satisfactory postoperative hearing improvement after CI despite receiving hearing and speech function training. In recent years, with the development of gene detection technology, preliminary results have been achieved in the study of deafness gene as the etiology of congenital deafness patients, and its influence on postoperative efficacy of CI has also been widely studied. In this paper, the correlation between deafness gene mutation and the postoperative efficacy of CI is reviewed. |
| Key words: Deafness gene Cochlear implant(CI) Postoperative efficacy |
