| 摘要: |
| ［摘要］ 目的 评价2型糖尿病社区药学服务干预的临床效果。方法 选取2型糖尿病患者300例，采取随机数字法分为干预组和对照组各150例。两组均给予常规2型糖尿病诊疗服务和糖尿病知识宣教工作，并定期随访和监测血糖；干预组同时加强用药指导、强化药物不良反应监测，建立定期随访预约服务，干预周期为6个月。观察两组患者干预前后的血糖（空腹血糖、餐后2 h血糖和糖化血红蛋白）水平、自我管理行为和药物不良反应等。结果 经6个月药学服务干预后，两组患者的空腹血糖、餐后2 h血糖和糖化血红蛋白较干预前下降（P<0.01）；生活方式、用药行为依从性，对糖尿病相关知识（生活方式、用药行为、自我监测、不良反应）认知率有不同程度提高（P<0.05或P<0.01），且干预组均优于对照组（P<0.05或P<0.01）；干预组、对照组的药物不良反应率分别为8.00%、16.67%，差异有统计学意义（P<0.05）。结论 社区药学服务干预能改善2型糖尿病患者的血糖水平，提高其自我管理能力，降低药品不良反应的发生率，对实现患者安全、有效用药具有重要的临床意义。 |
| 关键词: 糖尿病 社区药学服务 干预 疗效评价 |
| DOI：10.3969/j.issn.1674-3806.2017.03.22 |
| 分类号:R 587.1 |
| 基金项目: |
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| Effects of community pharmaceutical care on type 2 diabetes |
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ZHONG Jun-shan, CHEN Liu-huan, LI Mao-qing, et al.
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The Community Health Service Center of Jiangnan Street in Meijiang District Meizhou City, Guangdong 514021, China
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| Abstract: |
| ［Abstract］ Objective To evaluate the clinical effects of community pharmaceutical care on type 2 diabetes.Methods Three hundred patients with type 2 diabetes were sellected from the community health service center and were divided into the intervention group(n=150) and the control group(n=150). Both of the two groups were given the routine medical services and health education, and their blood glucose levels were monitored by a regular follow-up. The intervention group received an additional pharmaceutical care and monitoring of the adverse reaction for 6 months. The blood glucose, fasting blood sugar, 2 h postprandial blood glucose and glycosylated hemoglobin levels, self-management behavior and adverse reactions were compared between the two groups before and after the intervention.Results The levels of 2 h postprandial blood glucose, fasting glucose and glycosylated hemoglobin in both of the two groups were significantly lower 6 months after the pharmaceutical care(P<0.01); The rates of correct knowledge of lifestyle, medication compliance behavior and the related knowledge of diabetes mellitus were significantly improved in both of the two groups after the pharmaceutical care(P<0.05 or P<0.01), and the improvement of the intervention group were better than those of the control group(P<0.05 or P<0.01). The rate of adverse drug reactions of the intervention group was significantly lower than that of the control group(8.00% vs 16.67%)(P<0.05).Conclusion Individualized community pharmaceutical care can improve the blood sugar levels and the self- management ability of health in the patients with type 2 diabetes. |
| Key words: Diabetes Community pharmaceutical care Intervention Curative effect |
