| 摘要: |
| ［摘要］ 目的 调查广西艾滋病（HIV/AIDS）合并结核病（TB）双重感染情况，并分析其影响因素。方法 收集2013年广西某传染病医院就诊的1 086例艾滋病患者的临床资料，分析其HIV/TB双重感染情况，运用二分类Logistic回归模型进行TB/HIV双重感染影响因素分析。结果 1 086例艾滋病患者中，HIV/TB双重感染527例（48.53%）。其中单纯肺结核245例（46.49%），肺结核合并肺外结核197例（37.38%），单纯肺外结核85例（16.13%）。多因素Logistic回归分析显示，男性患者（OR=1.472，95%CI=1.056～2.054）、>50岁者（OR=1.477，95%CI=1.111～1.964）、CD4+ T淋巴细胞计数低者（OR=1.347，95%CI=1.022～1.776）及血小板计数较高者（OR=2.079，95%CI=1.360～3.179）更易感染TB。结论 广西HIV/AIDS患者TB的感染率较高，性别、年龄、血小板和CD4+ T淋巴细胞计数是其感染TB的危险因素，应根据患者的不同临床特征制定相应的防治措施。 |
| 关键词: 艾滋病 结核病 影响因素 |
| DOI：10.3969/j.issn.1674-3806.2017.04.01 |
| 分类号:R 512.91 |
| 基金项目:国家自然科学基金资助项目（编号：31360033,81560326)；广西科学研究与技术开发计划项目(编号：桂科攻14124003-1) |
|
| Study on HIV-TB coinfection in Guangxi and its influenced factors |
|
MENG Si-run, WU Feng-yao, CHEN Xiao-yu, et al.
|
|
Guangxi Key Laboratory of AIDS Prevention and Control, School of Public Health, Guangxi Medical University, Nanning 530021, China
|
| Abstract: |
| ［Abstract］ Objective To investigate tuberculosis(TB) and human immunodeficiency virus(HIV) coinfection in Guangxi and its influnenced factors.Methods 1 086 HIV/AIDS patients from a certain hospital for infectious diseases of Nanning, Guangxi were screened for TB/HIV coinfection. Logistic regression model was performed to analyze the factors that influenced TB and HIV coinfection.Results 48.53% of the 1 086 HIV/AIDS patients were coinfected with TB and HIV in which simple TB accounted for 46.49%, TB complicated with extrapulmonary TB accounted for 37.38%, and simple extrapulmonary TB accounted for 16.13%. Multivariate logistic regression analysis showed that there were four major risk factors of getting TB topped the list-male patients(OR=1.472, 95%CI=1.056～2.054), more than fifty years old(OR=1.477, 95%CI=1.111～1.964), lower CD4+ T lymphocytes cell count(OR=1.347, 95%CI=1.022～1.776) and higher platelet count(OR=2.079, 95%CI=1.360～3.179).Conclusion The infection rate of TB is high in the HIV patients of Guangxi. Sex, age, CD4+ T lymphocytes cell count and platelet count are the risk factors for HIV/AIDS patients. Different preventing measures should be given to the patients according to their different clinical features. |
| Key words: Acquired immune deficiency syndrome（AIDS） Tuberculosis（TB） Influenced factors |
