| 摘要: |
| ［摘要］ 目的 探讨同型半胱氨酸（Hcy）、脂蛋白（a）［LP（a）］和D-二聚体（D-D）联合检测对诊断急性脑梗死的价值。方法 选取急性脑梗死患者150例作为观察组，同期行健康体检者120名作为健康组，均检测Hcy、LP（a）、D-D。观察组根据美国国立卫生研究院卒中量表（NIHSS）评分分为3个亚组，分别为轻型亚组86例，中型亚组42例，重型亚组22例，比较各组Hcy、LP（a）、D-D检测结果。结果 中型亚组、重型亚组的Hcy、LP（a）、D-D水平高于轻型亚组，差异有统计学意义（P<0.05）。重型亚组Hcy、LP（a）、D-D水平与中型亚组比较差异有统计学意义（P<0.05）。健康组Hcy、LP（a）、D-D水平低于重型亚组，差异有统计学意义（P<0.05）。结论 Hcy、D-D、LP（a）三项指标均可反映脑梗死病情，三项指标联合检测可能更能反映急性脑梗死病情。 |
| 关键词: 同型半胱氨酸 脂蛋白（a） D-二聚体 诊断 急性脑梗死 |
| DOI：10.3969/j.issn.1674-3806.2017.04.22 |
| 分类号:R 741 |
| 基金项目: |
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| The value of combined detection of homocysteine, lipoprotein(a) and D-Dimer in the diagnosis of acute cerebral infarction |
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CHEN Shang-wu
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Department of Laboratory, the People′s Hospital of Tengxian County, Guangxi 543300, China
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| Abstract: |
| ［Abstract］ Objective To investigate the value of combined detection of homocysteine(Hcy), lipoprotein(a)［LP(a)］ and D-Dimer in the diagnosis of acute cerebral infarction.Methods One hundred and fifty cases with acute cerebral infarction were selected as the observation group, and 120 healthy people were taken as the healthy group, Hcy, LP(a) and D-Dimer were detected. According to the NIHSS scores, the observation group was divided into 3 subgroups, with 86 cases in the mild subgroup, 42 cases in the medium subgroup, and 22 cases in the severe subgroup. The relationship between Hcy, LP(a) and D-Dimer detection results was studied.Results The levels of Hcy, LP(a) and D-Dimer in the medium and severe subgroups were significantly higher than those in the mild subgroup(P<0.05). There were significant differences in Hcy, LP(a) and D-Dimer between the medium subgroup and the severe subgroup(P<0.05). The levels of Hcy, LP(a) and D-Dimer in the healthy group were significantly lower than those in the severe subgroup(P<0.05).Conclusion Hcy, D-Dimer and LP(a) can reflect the conditions of the patients with cerebral stroke. The combined detection of them is valuable for the diagnosis of acute cerebral infarction. |
| Key words: Homocysteine Lipoprotein(a) D-Dimer Diagnosis Acute cerebral infarction |
