| 摘要: |
| ［摘要］ 目的 观察胺碘酮治疗中老年人急性心肌梗死合并快速心室率心房颤动的临床疗效。方法 对2013-05～2016-05收治的60例发生心肌梗死的中老年患者，入院24 h内并发心室率>120次/mim快速心室率心房颤动的中老年患者，年龄48～78岁，给予胺碘酮静脉加口服治疗，观察临床疗效。结果 60例患者中51例（85%）在48 h转复为窦性心律，4例死亡，5例未转复，疗效显著，心室率下降明显（P<0.01），血压无明显变化（P>0.05）。不良反应：窦性心动过缓1例，长R-R间歇3例，血压下降1例，静脉炎1例，予停药或对症处理后均好转。56例患者出院后随访30 d内无一例死亡，无其他不良反应发生。结论 中老年人急性心肌梗死合并快速心室率心房颤动患者，应用胺碘酮静脉加口服治疗疗效显著、不良反应率低，值得临床推广应用。 |
| 关键词: 胺碘酮 中老年人 急性心肌梗死 快速心室率 心房颤动 |
| DOI：10.3969/j.issn.1674-3806.2017.06.21 |
| 分类号:R 542.2+2 |
| 基金项目: |
|
| Efficacy of amiodarone in patients with acute myocardial infarction complicated with rapid ventricular fibrillation |
|
PAN You-ping
|
|
Department of Cardiovascular Internal Medicine, Traditional Chinese Medicine Hospital of Lingshan County, Guangxi 535400, China
|
| Abstract: |
| ［Abstract］ Objective To observe the clinical effect of amiodarone on treatment of acute myocardial infarction(AMI) complicated with rapid ventricular rate and atrial fibrillation.Methods In the past 3 years, 60 elderly patients with myocardial infarction, aged 48 to 78 years, within 24 hours of hospitalization with rapid ventricular rate of atrial fibrillation more than 120 times per minute, were given intravenous and oral amiodarone therapy. The clinical effect was observed.Results In the 60 patients, 51 cases(85%) were converted to sinus rhythm at the end of 48 hours. 4 cases died and 5 cases were not converted, with a significantly better curative effect, and a significantly decreased ventricular rate(P<0.01), and no significant changes in blood pressure(P>0.05). For adverse reactions:sinus bradycardia occurred in 1 case, long R-R intermittent in 3 cases, decreased blood pressure in 1 case and phlebitis in 1 case, all of which were improved after drug withdrawal or symptomatic treatment. 56 patients were followed up for a period of 30 days after discharge from the hospital and none of them died.Conclusion Intravenous plus oral therapy of amiodarone has a significant curative effect and low adverse reaction for the elderly patients with acute myocardial infarction complicated with rapid ventricular fibrillation. |
| Key words: Amiodarone Middle-aged and elderly patients Acute myocardial infarction(AMI) Rapid ventricular rate Atrial fibrillation |
