| 摘要: |
| ［摘要］ 目的 探讨凝血相关指标在急性肺栓塞（APE）中的临床意义。方法 选择该院呼吸科2013～2015年住院的APE患者43例（病例组），并选择同期47名健康体检者作为对照组，采用全自动血凝分析仪对入选者凝血酶原时间（PT）、部分活化凝血活酶时间（APTT）、血浆纤维蛋白原（FIB）、凝血酶时间（TT）指标进行检测，观察首次住院及出院前凝血指标变化。结果 与对照组相比，病例组PT、APTT显著降低，FIB含量显著升高（P<0.05）。病例组治疗后PT、APTT显著升高，FIB含量显著降低（P<0.05）；但TT在各组中均无明显变化（P>0.05）。结论 凝血相关指标在急性肺栓塞的临床诊断及溶栓治疗中具有一定的指导意义。 |
| 关键词: 急性肺栓塞 凝血酶原时间 部分活化凝血活酶时间 血浆纤维蛋白原 凝血酶时间 |
| DOI：10.3969/j.issn.1674-3806.2017.08.26 |
| 分类号:R 563.5 |
| 基金项目: |
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| The changes of coagulation tests in patients with acute pulmonary embolism and its clinical value |
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LI Jun, KUANG Jun, LI Ting
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The changes of coagulation tests in patients with acute pulmonary embolism and its clinical value
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| Abstract: |
| ［Abstract］ Objective To investigate the clinical value of coagulation tests in the patients with acute pulmonary embolism.Methods 43 patients with acute pulmonary embolism(the observation group) and 47 healthy people(the control group) were collected from 2013 to 2015. The Pre-hospital coagulation tests（PT, APTT, FIB, TT） were detected by ACL 3000 coagulation analyzer, and the changes of coagulation indexes were observed at the first time of hospitalization and before hospiotal discharge.Results Compared with those in the control group, PT and APTT were decreased significantly and FIB was increased significantly in the observation group(P<0.05). In the observation group, compared with those before the treatment, the levels of PT and APTT were increased significantly and FIB was decreased after the treatment(P<0.05). There were no significant differences in the levels of TT between the two groups（P<0.05）.Conclusion Coagulation-related indicators have a certain clinical significance in the diagnosis and thrombolytic therapy of acute pulmonary embolism. |
| Key words: Acute pulmonary embolism(APE) Prothrombin time(PT) Activated partial thromboplastin time(APTT) Fibrinogen(FTB) Thrombin time(TT) |
