摘要: |
[摘要] 糖尿病肾病是糖尿病的主要微血管并发症之一,其发病机制仍未完全阐明,可能与糖代谢紊乱、炎症反应、遗传、血流动力学异常、氧化应激等多种因素有关,在治疗上主要通过饮食、血糖、血压、血脂的控制等方法来加以干预,以延缓病情进展和提高患者生活质量。该文就近年来关于糖尿病肾病的发病机制和治疗进展作一综述。 |
关键词: 糖尿病肾病 发病机制 治疗 研究进展 |
DOI:10.3969/j.issn.1674-3806.2017.10.30 |
分类号:R 587.1 |
基金项目: |
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Research progress in the pathogenesis and treatment of diabetic nephropathy |
YU Xiao-bo, YU Yong-zhuang
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Department of Endocrinology, the Third People′s Hospital of Hechi City, Guangxi 547000, China
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Abstract: |
[Abstract] Diabetic nephropathy is one of the main microvascular complications of diabetes. The pathogenesis of diabetic nephropathy is not yet completely clear. Some multiple mechanisms contributing to the pathogenesis of diabetic nephropathy, including sugar metabolism disorders, inflammatory reaction, genetic susceptibility, hemodynamic changes and cytokines. Its clinical treatments including the control of diet, plasma glucose, blood pressure and lipid should be done to delay disease progression and to improve the quality of life. The research progress in the pathogenesis and treatment of diabetic nephropathy is reviewed in this paper. |
Key words: Diabetic nephropathy Pathogenesis Treatment Research progress |