| 摘要: |
| ［摘要］ 阿尔茨海默病（Alzheimer′s disease，AD）是一种常见的神经系统变性疾病，炎症免疫反应在AD发病机制中具有重要作用。近年来Ghrelin被广泛研究，成为炎症反应及其控制手段的热门研究，该文就与AD炎症反应发病机制相关的Ghrelin、Toll样受体和炎症因子的研究进展进行综述。 |
| 关键词: 阿尔茨海默病 Ghrelin Toll样受体4 炎症因子 炎症反应 |
| DOI：10.3969/j.issn.1674-3806.2018.05.33 |
| 分类号:R 741 |
| 基金项目:广西医疗卫生适宜技术开发与推广应用项目(编号：S201626)；广西卫生医药科研课题（编号：Z2016250） |
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| Advances in pathogenesis of inflammatory response to Alzheimer′s disease |
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HUANG Dong-ming, HU Cai-you
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Department of Neurology, Jiangbin Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Alzheimer′s disease(AD) is a common neurodegenerative disorder, and inflammatory immune response plays an important role in the pathogenesis of AD. Ghrelin has been widely studied in recent years, and becomes a research hotspot. The research progress of inflammatory reaction and its control methods related to the pathogenesis of AD inflammation Ghrelin, Toll-like receptors and inflammation factors are reviewed in this paper. |
| Key words: Alzheimer′s disease Ghrelin Toll-like receptor 4 Inflammatory cytokines Inflammatory response |
