引用本文:陈锦贤,林楚标,陈伟龙.支撑喉镜联合鼻内镜电凝治疗早期声门型喉癌的嗓音分析及声带新生情况观察[J].中国临床新医学,2018,11(6):535-538.
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支撑喉镜联合鼻内镜电凝治疗早期声门型喉癌的嗓音分析及声带新生情况观察
陈锦贤,林楚标,陈伟龙
515800 广东,汕头市澄海区人民医院耳鼻咽喉头颈外科
摘要:
[摘要] 目的 探讨支撑喉镜联合鼻内镜电凝切除病变声带治疗早期声门型喉的嗓音分析及声带新生情况。方法 选取该院2012-01~2016-08诊治早期声门型喉癌患者100例,按照数字表法随机分为观察组和对照组,各50例。对照组接受喉裂开声带切除或喉部分切除术,观察组接受支撑喉镜联合鼻内镜电凝切除病变声带治疗,根据随访6个月有无声带新生将其分为声带新生组(35例)及无声带新生组(65例),比较两组人群声学特征。结果 术前两组患者参数基顿(FO)、最长发音时间(MPT)比较,差异无统计学意义(P>0.05),术后2周、1、3个月观察组FO均低于对照组,MPT均高于对照组,差异有统计学意义(P<0.05);观察组声带新生率58.00%(29/50)高于对照组的12.00%(6/50),无声带新生组FO高于声带新生组,MPT低于声带新生组,差异有统计学意义(P<0.05)。结论 支撑喉镜联合鼻内镜电凝切除病变声带治疗早期声门型喉癌,损伤较小,利于患者术后声带新生及术后嗓音恢复,值得临床作进一步推广。
关键词:  支撑喉镜  鼻内镜电凝切除  早期声门型喉癌  嗓音  声带新生
DOI:10.3969/j.issn.1674-3806.2018.06.04
分类号:R 767
基金项目:汕头市医疗科技计划项目(编号:[2014]62号)
Voice analysis and vocal cords observation in early stage laryngeal cancer patients after supported laryngoscopy combined with endoscopic electrocoagulation
CHEN Jin-xian, LIN Chu-biao, CHEN Wei-long
Department of Otolaryngology Head and Neck Surgery, the People′s Hospital of Chenghai District, Shantou City, Guangdong 515800, China
Abstract:
[Abstract] Objective To discuss the voice analysis and vocal cords observation in early stage laryngeal cancer patients after supported laryngoscopy combined with endoscopic electrocoagulation. Methods 100 patients with early stage laryngeal cancer were selected from January 2012 to August 2016 in our hospital and randomly divided into the observation group and the control group, with 50 cases in each group. The control group received laryngeal fissure vocal cord excision or laryngectomy. The observation group received supported laryngoscopy and endoscopic electrocoagulation of diseased vocal cords. The patients were divided into vocal cord neogenesis group(n=35) and vocal cord non-neogenesis group(n=65) according to different vocal cords. The acoustic characteristics were compared between the two groups. Results There were no significant differences between the two groups in FO and MPT before operation(P>0.05). FO was lower and MPT was higher in the observation group than those in the control group 2 weeks, 1 and 3 months after surgery(P<0.05). The rate of vocal cord neogenesis in the observation group(58.00%) was higher than that in the control group(12.00%). FO was higher and MPT was lower in the vocal cord non-neogenesis group than in the vocal cord neogenesis group(P<0.05). Conclusion Supported laryngoscopy combined with endoscopic electrocoagulation causes small lesions and is conducive to regenerating the vocal cords for the patients with early stage laryngeal cancer.
Key words:  Supported laryngoscopy  Endoscopic electrocoagulation  Early stage laryngeal cancer  Voice  Vocal cords