引用本文:黄文亮,王志勇,付升旗,周 山.基于DWI产生的ADC值与宫颈癌病理学类型及分化程度的关系[J].中国临床新医学,2018,11(7):640-642.
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基于DWI产生的ADC值与宫颈癌病理学类型及分化程度的关系
黄文亮,王志勇,付升旗,周 山
462300 河南,漯河医学高等专科学校第二附属医院(黄文亮,周 山);453003 河南,新乡医学院解剖学教研室(王志勇,付升旗)
摘要:
[摘要] 目的 探讨基于弥散加权成像(DWI)产生的表观扩散系数(ADC)值与宫颈癌组织病理学类型及分化程度的关系。方法 对43例经病理证实宫颈癌患者行常规MRI及DWI扫描,b值取0及1 000 s/mm2,并测量宫颈癌ADC值,分析ADC值与宫颈癌组织病理学类型及分化程度相关性。结果 宫颈鳞癌平均ADC值(×10-3mm2/s)为(0.78±0.09),腺癌平均ADC值为(0.94±0.14),两者差异亦存在统计学意义(P<0.05);宫颈癌高分化组13例,中分化组21例,低分化组9例,ADC值分别为(1.04±0.14)、(0.85±0.11)、(0.72±0.07),组间差异有统计学意义(P<0.01)。结论 ADC值在一定程度上提示宫颈癌组织病理学类型及分化程度,可作为评估宫颈癌组织病理学类型及分化程度理想手段之一。
关键词:  弥散加权成像  表观扩散系数  宫颈癌  病理学
DOI:10.3969/j.issn.1674-3806.2018.07.04
分类号:R 445
基金项目:漯河医学高等专科学校临床资助项目(编号:2015-S-LMC018)
Correlation between MRI_DWI and pathological feature and degree of cervical cancer
HUANG Wen-liang, WANG Zhi-yong, FU Sheng-qi, et al.
The Second Affiliated Hospital of Luohe Medical College, Henan 462300, China
Abstract:
[Abstract] Objective To investigate the correlation between apparent diffusion coefficient(ADC) derived from diffusion-weighted imaging(DWI) and the pathological feature and degree of cervical cancer. Methods Conventional MRI(magnetic resonance imaging) and DWI(the range of diffusion factor from 0 to 1 000 s /mm2) were performed in forty-three patients with advanced cervical cancer, and the ADC values of them were measured. The correlation was analyzed between ADC and the pathological feature and degree of cervical cancer. Results There were statistic differences in the ADC values between squamous carcinoma (0.78±0.09)×10-3 mm2/s and adenocarcinoma (0.94±0.14)×10-3 mm2/s of cervical cancer(P<0. 05). There was a negative correlation between ADC values of cervical cancer and grades of the tumor(r=-0.676, P=0.008). Conclusion ADC values may be an ideal tool to evaluate the pathological feature and degree of cervical cancer.
Key words:  Diffusion-weighted imaging(DWI)  Apparent diffusion coefficient(ADC)  Cervical cancer  Pathology