| 摘要: |
| ［摘要］ 自20世纪80年代至今，自体造血干细胞移植已成为一种治疗急性髓系白血病（AML）的主要疗法。目前自体造血干细胞移植成为因难以找到人类白细胞抗原（HLA）配型相合者而不能行异基因造血干细胞移植的主要治疗手段。该文综述了自体造血干细胞移植在低危、中高危AML及难治性或复发性AML患者中的治疗进展，追踪了降低自体造血干细胞移植治疗AML复发率的策略。 |
| 关键词: 自体造血干细胞 移植 急性髓系白血病 人类白细胞抗原 |
| DOI：10.3969/j.issn.1674-3806.2018.07.28 |
| 分类号:R 733.71 |
| 基金项目:广西卫计委科研课题（编号：Z2014357） |
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| Therapy progress of autologous hematopoietic stem cells transplantation on acute myeloid leukemia |
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CHEN Yong-sheng, HUANG Qin, YIN Xiao-lin
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Autologous hematopoietic stem cell；Transplantation；Acute myeloid leukemia；Human leucocyte antigen
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| Abstract: |
| ［Abstract］ Since 1980s, autologous hematopoietic stem cells transplantation(auto-HSCT) has developed as one of the main therapies for hundreds of thousands of patients with acute myeloid leukemia(AML), for whom HLA-matched related donor can not be found and allogeneic hematopoietic stem cell transplantation was not done. This article aims at reviewing the progress of auto-HSCT in treating the AML patients with low, intermediate and high risk factors. and the refractory or recurrent AML, and reviewing the strategy about decreasing the relapse of auto-HSCT therapy. |
| Key words: Autologous hematopoietic stem cell Transplantation Acute myeloid leukemia Human leucocyte antigen |
