| 摘要: |
| ［摘要］ 目的 观察益肾消痛丸联合体外冲击波治疗早中期肝肾不足型股骨头坏死的临床疗效。方法 选取河南省中医院关节科符合早中期股骨头坏死患者50例（79髋），按照随机数字表分为两组，治疗组25例（41髋），对照组25例（38髋）。治疗组采用益肾消痛丸联合体外冲击波疗法，对照组采用常规西药联合体外冲击波疗法。运用视觉模拟评分法（VAS）、髋关节Harris评分表来观察记录患者治疗前后评分，评定两组临床疗效，并在治疗前、治疗后及治疗后6个月行X线及MRI检查。结果 经治疗后，治疗组临床疗效优于对照组（Z=-2.154，P=0.031），治疗组的总有效率为92.68%，对照组的总有效率为76.32%，两组患者治疗后的VAS评分及Harris评分较治疗前均有改善（P<0.05），但治疗组治疗后的VAS评分及Harris评分较对照组相比改善更为明显（P<0.05）。结论 益肾消痛丸联合体外冲击波治疗早中期肝肾不足型股骨头坏死有较好的临床疗效，可以很好地预防股骨头坏死的进一步发展或延缓股骨头坏死塌陷的时间。 |
| 关键词: 肝肾亏虚 股骨头坏死 未塌陷 益肾消痛丸 冲击波 |
| DOI：10.3969/j.issn.1674-3806.2018.08.02 |
| 分类号:R 681 |
| 基金项目:河南省教育厅科学技术研究重点项目（编号：14A360023）；河南省郑州市普通科技攻关项目（编号：20150289）；河南中医药大学苗圃科研基金项目（编号：MPYJS-2018-15） |
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| Clinical observation of Yishen Xiaotong pills combined with shock wave in treatment of femoral head necrosis on early or medium-term stage |
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YU Peng, WU Sheng-chao, WANG Shang-zeng
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The Second Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China
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| Abstract: |
| ［Abstract］ Objective To observe the clinical effect of Yishen Xiaotong pills combined with extracorporeal shock wave on treatment of femoral head necrosis on early or medium-term stage caused by liver and kidney insufficiency. Methods 50 cases(79 hips) of osteonecrosis of the femoral head on the early or medium-term stage caused by liver and kidney insufficiency were selected from the Department of Arthrology, Henan Province Hospital of Traditional Chinese Medicine. According to the random number table, 50 cases were divided into two groups: treatment group(25 cases, 41 hips) and control group(25 cases, 38 hips). The treatment group was treated with Yishen Xiaotong pills combined with extracorporeal shock wave therapy, while the control group was treated with routine western medicine combined with extracorporeal shock wave therapy. TheVisual Analogue Score(VAS) and the hip joint Harris scale(Harris) were recorded to evaluate the clinical efficacy of the two groups before and after treatment. X-ray and MRI were performed on the patients before and after treatment and 6 months after treatment. Results After treatment, the effect of the treatment group was better than that of the control group(Z=-2.154, P=0.031). The total effective rate was 92.68% in the treatment group and 76.32% in the control group. The VAS scores and Harris scores were improved in both of the two groups after treatment(P<0.05). However, the improvement of the VAS scores and Harris scores in the treatment group were better than those in the control group(P<0.05). Conclusion Yishen Xiaotong pills combined with extracorporeal shock wave has good clinical effect on the treatment of femoral head necrosis on early or medium-term stage caused by liver and kidney insufficiency. It can prevent the further development of femoral head necrosis or delay the time of collapse of femoral head necrosis. |
| Key words: Liver and kidney insufficiency Osteonecrosis of the femeral head(ONFH) No collapsing Yishen Xiaotong pills Extracorporeal shock wave(ESW) |
