| 摘要: |
| 目的：分析围绝经期女性子宫内膜息肉病理类型与性激素的相关性。方法：回顾性分析132例2014年1月~2017年6月间行子宫内膜息肉手术的围绝经期妇女的临床资料,分析子宫内膜息肉病理类型与性激素指标间的相关性,评估性激素相关指标在子宫内膜息肉病变进展中的作用。结果：134例患者的子宫内膜息肉病理组织类型为：单纯性增生92例(68.66%),复杂性增生36例(26.87%),伴非典型性增生性单纯性增生4例(2.98%),伴非典型性增生性复杂性增生2例(1.49%)。病理组织类型与患者卵泡雌激素均值、黄体生成素均值、泌乳素均值、孕激素均值无明显相关(P>0.05)；但它与雌激素均值、年龄呈线性正相关(r1=0.293,p1=0.001；r2=0.355,p2=0.000),雌激素越高、年龄越大,组织恶变倾向越大；与雄激素均值呈线性负相关(r=-0.299,p=0.000),雄激素的下降增加了组织恶变的风险。结论：雌激素、雌激素与雄激素结合,在预测围绝经期子宫内膜息肉的恶变风险有一定的参考价值,它在发现子宫内膜息肉恶变倾向上比组织病理检查更具无创性,值得临床上进一步深入探讨。。 |
| 关键词: 子宫内膜息肉 激素 病理类型 围绝经期 |
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| Correlation analysis of different pathological types of endometrium polyps in perimenopausal women with sex hormones |
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First Maternal and Child Health Care Hospital of Huizhou City
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| Abstract: |
| Objective: to analyze the correlation between the pathological types of endometrium polyps and sex hormone in women with menopause peri menopause.Methods: a retrospective analysis of the clinical treatment of 132 cases of perimenopausal women who was taken the operation of endometrial polyps in January 2014~2017 June was reviewed. The correlation between the different pathological types of endometrium polyps and the sex hormone indexes was analyzed in order to evaluate the role of sex hormone related indicators in the development of endometrium polyps. Results: The pathological type of endometrium polyps in 134 patients was： simple hyperplasia 92 Case (68.66%), complex hyperplasia 36 Cases (26.87%), with atypical hyperplasia of simple hyperplasia 4 Cases (2.98%), accompanied by atypical hyperplastic hyperplasia 2 Cases (1.49%)。 there was no significant correlation between the pathological types and the mean follicular estrogen, the mean luteinizing hormone, the mean prolactin hormone and the mean progesterone of the patients (P>0.05)；there was a positive linear correlation between the pathological type and the mean estrogen and age(r1=0.293,p1=0.001；r2=0.355,p2=0.000),when the mean estrogen was higher and the age was older, the tendency of the malignant transformation of the tissue was greater; and there was a negative correlation between the mean androgen and pathological type(r=-0.299,p=0.000),when the androgens droped, it would increase the risk of tissue malignancy. Conclusion: The combination of estrogen and androgen has a certain reference value in predicting the risk of malignant transformation of endometrial polyps in perimenopausal period. It is more noninvasive in detecting the malignant transformation tendency of endometrial polyps than in histopathological examination. It is worth further exploring in clinic. |
| Key words: endometrium polyps hormone pathological type Perimenopause |
