引用本文:王英,肖信,黄惠瑶,卢海燕,洪华丽.晶星900光学生物测量仪测量近视患者眼轴及中央角膜厚度的准确性评价[J].中国临床新医学,0,():-.
Wang ying,Xiao Xin,Huang Hui-yao,Lu Hai-yan,Hong Hua-li.晶星900光学生物测量仪测量近视患者眼轴及中央角膜厚度的准确性评价[J].中国临床新医学,0,():-.
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晶星900光学生物测量仪测量近视患者眼轴及中央角膜厚度的准确性评价
王英, 肖信, 黄惠瑶, 卢海燕, 洪华丽
广西壮族自治区人民医院
摘要:
目的 评价晶星900光学生物测量仪测量近视患者眼轴长度(AL)及中央角膜厚度(CCT)的准确性。方法 选取在广西视光中心就诊的近视患者48例(96眼),年龄18~45岁,等效球镜-(1.0~6.75)D。采用晶星900和A超测量AL,用晶星900、A超和Pentacam测量CCT,应用配对t检验比较不同方法测量结果的差异,采用Pearson相关分析评估不同仪器测量结果的相关性,Bland-Altman分析评价不同方法测量结果的一致性。结果 晶星900和A超测得的AL分别为:(25.21 ± 1.18) mm、(25.09 ± 1.17) mm,两者比较差异有统计学意义(t=-4.911, p<0.01),两者间存在统计学意义的相关性(r=0.982,p<0.01),95%一致性界限为(-0.31~0.10) mm。 晶星900、A超和Pentacam测得的CCT分别为:(532.55 ± 24.09) μm、(530.03 ± 23.39) μm、(537.64 ± 23.75) μm。三者间两两比较差异均有统计学意义(t=-5.299、-8.460、-5.766,p均<0.01),Pearson相关分析显示晶星900测得的AL与A超(r=0.985, p<0.01)、Pentacam (r=0.956, p<0.01)的结果存在正相关,其三者测量CCT的95%界限:A超与晶星900为(-10.6~6.0)μm、 晶星900与pentacam 为(-14.7~8.4) μm、A超与Pentacam为 (-14.8~5.2) μm。 结论 晶星900与A超所测AL相关性好;晶星900与A超、Pentacam所测量CCT均有明显相关性,其中晶星900与金标准的A超所测得的CCT一致性较好。晶星900可以作为近视患者AL和CCT的非接触式测量工具之一。
关键词:  眼轴  中央角膜厚度  光学生物测量  近视  准确性
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基金项目:广西自然科学(编号:2015GXNSFBA139148)
The accuracy of Lenstar 900 optical biometry for axial length and central corneal thickness in myopia
Wang ying, Xiao Xin, Huang Hui-yao, Lu Hai-yan, Hong Hua-li
People’s Hospital of Guangxi Zhuang Autonomous Region
Abstract:
Objective To evaluate the accuracy of Lenstar 900 optical biometry for measurement of axial length and central corneal thickness in myopia. Methods 48 myopic participants (96 eyes), aged 18~45 years, were recruited from the visual science and optometry center of Guangxi with spherical equivalent (SE) varied from -1.00~-6.75 D. Axial Length (AL) was measured by Lenstar 900 and A-scan, and Central Corneal Thickness (CCT) was measured using Lenstar 900, A-scan and Pentacam. The paired t-test was used to compare the difference of the measured results of different instruments; Pearson correlation analysis and Bland-Altman analysis were used to evaluate the correlation and the consistency of the measured results of different methods. Results: The AL measured by Lenstar 900 and A-scan were (25.21 ± 1.18) and (25.09 ± 1.17) mm. There were statistically significant differences in the AL measured by Lenstar 900 and A-scan (t=-4.911, p<0.01). There was a significant correlation between the AL by Lenstar 900 and the AL by A-scan (r=0.982, p<0.01), the 95% limit of agreement (LOA) was (-0.31~0.10) mm. The CCT measured by Lenstar 900, A-scan and Pentacam were (532.55±24.09) μm, (530.03±23.39) μm, (537.64±23.75) μm respectively. There were significant differences in the pairwise comparison among three method (t=-5.299, -8.460, -5.766, all p<0.01), Pearson correlation analysis showed the AL measured by Lenstar 900 was positively correlated with the results of A-scan (r=0.985, p<0.01), and the results of Pentacam (r=0.956, p<0.01). The 95% LOA of CCT were (-10.6~6.0) μm for A-scan versus Lenstar 900, (-14.7~8.4) μm for Lenstar 900 versus and Pentacam, and (-14.8~5.2) μm for A-scan and Pentacam respectively. Conclusion: AL measured by Lenstar 900 was significant correlated with that of ultrasound A-scan; Similarly, The CCT measured by Lenstar 900 was also showed significant correlated with that of ultrasound A-scan and Pentacam. The CCT by Lenstar 900 showed satisfactory consistency with that of the gold standard ultrasound A-scan. The Lenstar 900 can be used as one of the non-contact measurement tools for AL and CCT in myopia. the gold standard A ultrasound. The Lenstar LS 900 can be used as one of the non-contact measurement tools for AL and CCT in myopia.
Key words:  Axial length  Central corneal thickness  Optical biometry  Myopia  Accuracy