| 引用本文: | 李琼香,郭艾灵,翁敏.尿毒症肌少症的研究进展[J].中国临床新医学,0,():-. |
| Li Qiongxiang,Guo Ailing,Weng Min.尿毒症肌少症的研究进展[J].中国临床新医学,0,():-. |
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| 摘要: |
| 肌少症,或称肌肉减少症,是指与增龄相关的进行性的肌量减少和或肌强度下降或肌肉生理功能减退。慢性肾脏病患者由于食欲降低、蛋白摄入减少、慢性炎症、体内存在代谢性酸中毒、蛋白质-能量消耗等,继而出现肌肉力量降低、选择性肌肉结构改变和明显的肌肉萎缩,称之为尿毒症肌少症。肌少症严重降低了透析患者的生活质量、增加致残率及死亡率等,及早发现、诊断及防治肌少症对提高尿毒症患者的生存质量至关重要。该文就尿毒症肌少症研究进展进行综述。 |
| 关键词: 尿毒症 肌少症 慢性肾脏病 |
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| Reserch progress of uraemic sarcopenia |
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Li Qiongxiang,Guo Ailing,Weng Min
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Department of Nephrology,the first Affiliated Hospital of Kunming Medical University
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| Abstract: |
| Sarcopenia is a progressive disease, associated with physiological aging process and defined by the reduction of the muscle mass, strength and/or function. Patients with chronic kidney disease due to decreased appetite ,low protein intake ,chronic inflammation, metabolic acidosis, protein-energy wasting, etc., followed by decreased muscle strength, selective muscle structure changes and significant muscle atrophy, called uraemic sarcoprnia. Sarcopenia severely reduces the quality of life, induces disability and mortality of dialysis patients. Early detection, diagnosis and prevention of sarcopenia are essential for improving the quality of life of uraemic patients. The aim of this review was to summarise the current understanding of uraemic sarcopenia. |
| Key words: uremia sarcopenia chronic kidney disease |
