引用本文: | 刘淑红,周英发,贾萌萌,农文志,刘芳,马艳萍,程序.放大内镜结合窄带成像对胃浅表隆起性低级别腺瘤与早期癌的诊断价值[J].中国临床新医学,0,():-. |
| LIU Shuhong,ZHOU Yingfa,JIA Mengmeng,NONG Wenzhi,LIU Fang,MA Yanping,CHENG Xu..放大内镜结合窄带成像对胃浅表隆起性低级别腺瘤与早期癌的诊断价值[J].中国临床新医学,0,():-. |
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摘要: |
目的:研究放大内镜结合窄带成像(magnifying endoscopy and narrow band imaging,ME-NB)对胃浅表隆起性病变低级别腺瘤(low grade adenoma, LGA)与早期胃癌(early gastric carcer, EGC)的诊断价值。方法:选取在2016年9月至2018年5月在郑州大学第二附属医院行无痛胃镜检查的58例胃浅表隆起性病变为研究对象。用传统的白光成像(White light imaging ,C-WLI)将EGC的内镜标准定义为颜色发红,使用M-NBI用带分界线的不规则微血管图案或带有分界线的不规则微表面图案即VS分型为诊断标准,测定了C-WLI和M-NBI诊断这58个病变的敏感性、特异性和准确性。结果:C-WLI与M-NBI的敏感性、特异性和准确性为64%、90%、72%;94%、90%和93%。敏感度和准确性差异显著(P<0.05),而特异度差异无统计学意义(P>0.05)结论:M-NBI有助于鉴别浅表隆起性胃癌和腺瘤。 |
关键词: 窄带成像技术 放大内镜 活检 病理。 |
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基金项目:1.高清晰放大NBI胃镜联合肿瘤分子标记对胃癌高危人群预警的临床研究(18A320067)2.高清晰放大窄带成像(ME-NBI)胃镜联合肿瘤标记对食管癌高危人群预警的临床研究(182102310361)。通讯作者,男,1969年10月生,博士,副主任医师,研究方向消化道肿瘤,E-mail:yfzhou69@163.com。 |
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Magnifying endoscopy with narrow-band imaging is useful in the differential diagnosis between low-grade adenoma and early cancer of superficial elevated gastric lesions |
LIU Shuhong, ZHOU Yingfa, JIA Mengmeng, NONG Wenzhi, LIU Fang, MA Yanping, CHENG Xu.
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The second Affiliated Hospital of Zhengzhou University Zhengzhou 450014
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Abstract: |
Objective:To study the diagnostic value of magnifying endoscopy with narrow-band imaging in the diagnosis of low grade adenoma and early carcinoma of gastric superficial elevated gastric lesions. method From September 2016 to May 2018, 58 cases of superficial protuberance lesions of stomach were examined by painless gastroscopy in the second affiliated Hospital of Zhengzhou University.We defined the endoscopic criteria for early cancer as red coloring using conventional white light imaging (C-WLI), and an irregular microvascular pattern with a demarcation line, or irregular microsurface pattern with a demarcation line, using M-NBI. We determined the sensitivity, specificity and accuracy of C-WLI and M-NBI in the diagnosis of these 53 lesions. Results The sensitivity, specificity, and accuracy of C-WLI versus M-NBI were 64 %versus 94 % , 90 % versus 90 % , and 72 % versus 93 % , respectively. There was significant difference in sensitivity and accuracy (P < 0.05), but there was no significant difference in specificity (P < 0.71).Conclusion M-NBI appears to be useful in differentiating between cancerous and adenomatous superficial elevated lesions of the stomach |
Key words: Narrow band imaging Magnifying endoscopy Biopsy Pathology. |