| 引用本文: | 杨珞,张艳利,薛国军,陈欢,杨光伦.甲状腺髓样癌的临床特征及检测血清降钙素的意义[J].中国临床新医学,0,():-. |
| Yang Luo,Zhang Yan-li,Xue Guo-jun,Chen Huan,Yang Guang-lun.甲状腺髓样癌的临床特征及检测血清降钙素的意义[J].中国临床新医学,0,():-. |
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| 摘要: |
| [摘要] 目的 分析甲状腺髓样癌的临床特征及检测血清降钙素的意义，为临床诊断、治疗提供参考。方法 回顾性分析重庆医科大学附属第一医院2011-1~2016-9收治的甲状腺髓样癌患者共41例病例资料。患者均行手术治疗。分析术前血清降钙素水平与肿瘤大小、包膜是否侵犯、淋巴结转移、远处转移、肿瘤分期之间的关系。结果 35例患者术前血清降钙素水平升高，血清降钙素水平与临床分型、肿瘤大小、病灶单多等无统计学意义（P＞0.05）。但肿瘤有包膜侵犯者较无包膜侵犯者，有淋巴结转移者较无淋巴结转移者，III-IV期患者较I-II期患者，术前血清降钙素水平显著增高（P＜0.05）。结论 术前降钙素水平与肿瘤包膜是否受侵、淋巴结转移、临床分期有关，提示血清降钙素水平可为术前诊断、手术方式的选择、评估预后和检测复发转移等提供参考。
[关键词] 甲状腺髓样癌；降钙素；临床特点；相关性 |
| 关键词: 甲状腺髓样癌 降钙素 临床特点 相关性 |
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| Clinical features of medullary thyroid carcinoma and significance of detecting blood serum calcitonin |
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Yang Luo,Zhang Yan-li,Xue Guo-jun,Chen Huan,Yang Guang-lun
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Department of Endocrine and Breast Surgery,the First Affiliated Hospital of Chongqing Medical University
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| Abstract: |
| Objective ：To analyze the clinical characteristics of medullary thyroid carcinoma and the significance of serum calcitonin detection, so as to provide reference for clinical diagnosis and treatment. Methods ：41 patients with medullary thyroid cancer admitted to the First Affiliated Hospital of Chongqing Medical University from January 2011 to September 2016 were retrospectively analyzed. All patients underwent surgical treatment. The relationship between preoperative serum calcitonin level and tumor size, capsule invasion, lymph node metastasis, distant metastasis and tumor stage was analyzed. Results ：Preoperative serum calcitonin level was elevated in 35 patients, but there was no statistical significance between serum calcitonin level and clinical classification ,tumor size, single or multiple lesions(P > 0.05). However patients with tumor envelop invasion compared with those without tumor envelop invasion, patients with lymph node metastasis compared with those without lymph node metastasis and patients with stage III-IV compared with those in stage I-II, preoperative serum calcitonin level was significantly increased(P＜0.05).
Conclusion： The level of calcitonin before surgery is related to whether the tumor capsule is invaded, lymph node metastasis and clinical stage, suggesting that serum calcitonin level can provide reference for preoperative diagnosis, selection of methods, evaluation of prognosis and detection of recurrence and metastasis. |
| Key words: Medullary thyroid carcinoma Calcitonin Clinical characteristics Correlation |
