摘要: |
[摘要] 蛋白Z是一种维生素K依赖性蛋白,作为蛋白Z依赖的蛋白酶抑制剂(ZPI)的辅因子,在磷脂和钙离子存在的条件下,能够抑制因子Xa, ZPI也能抑制因子Ⅺa 。蛋白Z,ZPI与血栓性疾病中的关系已有初步研究。 |
关键词: 血浆蛋白Z 蛋白Z依赖性蛋白酶抑制剂 凝血 血栓形成 |
DOI: |
分类号:R 552 |
基金项目: |
|
The role of the protein Z and protein Z-dependent protease inhibitor in thrombotic diseases |
HUANG Chun-yu, WANG Le-min
|
The Affiliated Tongji Hospital of Tongji University.Shanghai 200065, China
|
Abstract: |
[Abstract] Protein Z is a vitamin K-dependent protein, a cofactor for dependent protease inhibitors (ZPI), can inhibit factor Ⅺa in the presence of phospholipid and calcium ions; ZPI can inhibit protein Z and Ⅺa,There are preliminary studies on the relationship between ZPI with thrombotic disease. |
Key words: Protein Z Protein Z dependent protease inhibitor Coagulation Thrombosis |