| 摘要: |
| ［摘要］ 目的 调查了解念珠菌尿病人临床特点并进行回顾性分析，帮助临床正确解读念珠菌尿结果。方法 用无菌方法留取病人中段尿进行定量培养，将培养结果和病人资料输入WHONET5.4软件，结合临床资料对念珠菌尿患者进行回顾性分析。结果 2007-01～2008-06我院住院和门诊尿标本中分离念珠菌76株, 检出率最高的念珠菌是白色念珠菌(48.7%)；念珠菌尿病人主要分布在内外科ICU病房，占61.8%；念珠菌尿中白细胞增高者占65.8%，年龄>60岁的占67.1%；念珠菌尿病人中使用广谱高效抗生素者占100%；留置尿管或放置支架者占97.4%；念珠菌病人以脑血管意外为主。结论 念珠菌尿以白色念珠菌为主, 念珠菌尿的危险因素包括留置尿管、脑血管意外、使用抗生素、老龄、潜在的尿路畸形、糖尿病、恶性肿瘤、慢性肾功能不全（CRI）等。念珠菌尿可能仅表示真菌的定植而不能确定为侵袭性真菌感染，大部分念珠菌尿患者为无尿路感染症状，无需局部或全身性的抗真菌治疗。 |
| 关键词: 念珠菌尿 留置尿管 抗生素 侵袭性真菌感染 |
| DOI： |
| 分类号:R 446.5 |
| 基金项目: |
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| Retrospective analysis on the candiduria from 76 urine samples |
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CHEN Xing-chun, ZHAO Li, LIN Wei, et al.
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People′s Hospital of Guangxi Zhuang Autonomous Region，Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To explore the clinical characteristic of patients with candiduria., and to provide information to guide the clinician in the treatment of candiduria.Methods A retrospective analysis was made on the candiduria and their clinical data during the period of Jan. 2007 to June 2008 with WHONET 5.4 software.Results The predominant causative organism in candiduria is candida albicans (48.7%), the most patients are from intensive care units(61.8%).Conclusion Risk factors for candiduria included urinary indwelling catheters, cerebrovascular accident, use of antibiotics, elderly age, underlying genitourinary tract abnormality, malignant tumor, CRI, presence of diabetes mellitus. Presence of candiduria may represent only colonization and there are no consistent diagnostic criteria to define invasive fungal infection.Most cases are asymptomatic, and does not require local or systemic antifungal therapy. |
| Key words: Candiduria Indwelling urinary catheter Antibiotics Invasive fungal infection |
