| 摘要: |
| ［摘要］ 目的 观察巴氯芬对脑卒中后偏瘫患者肌痉挛的治疗效果及不良反应。方法 脑卒中后的偏瘫住院患者60例, 均给予巴氯芬口服并结合康复训练3～6个月。服药前、服药中每1个月检查1次血尿常规及肝、肾功能。按修订的Ashworth评分法评定肌张力, 按Fugl-Meyer运动量表(FMMS)评定患者的运动功能。结果 60例患者中显效3例(5.0%), 有效27例(45.0%), 好转24例(40.0%), 无效6例(10.0%), 总有效率为90.0%。FMMS从(29.91±7.63)上升为(58.18±8.32)(P<0.01)。未见明显的毒副作用。结论 巴氯芬结合康复训练能明显改善脑卒中偏瘫肢体的痉挛状态，提高运动功能。 |
| 关键词: 脑卒中 肌痉挛 巴氯芬 康复训练 |
| DOI：10.3969/j.issn.1674-3806.2009.06.37 |
| 分类号:R 743.3 |
| 基金项目: |
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| Effect of baclofen combined with rehabilitation therapy on poststroke spasticity |
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CHEN Xiu-qiong, YANG Chu-yu, XU Wei, et al.
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The Department of Rehabilitation Medicine, Jiangbin Hospital of Guangxi, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To study the effect of baclofen with rehabilitation therapy on poststroke spasticity. Methods Sixty patients accepted baclofen with rehabilitation for 3～6 months. Blood and urine routine test, hepatic and renal function were monitored before and every 1 months after treatment. Modified Ashworth scale was used for evaluation of the spasticity and Fugl-Meyer Motor Scale (FMMS) was used for evaluation of the motor function.Results Their muscular tension was significantly improved (P<0.01) after treatment, as well as the FMMS (P< 0.01). 3 patients were very effective, 27 patients were effective, 24 patients were improved, 6 patients were not effective. No side-effect was observed.Conclusion Baclofen combined with rehabilitation can effectively relieve spasticity and improve the motor function of the stroke patients with spastic hemiplegia. |
| Key words: Stroke Spasticity Baclofen Rehabilitation |
