| 摘要: |
| ［摘要］ 目的 探讨联合检测血清甲胎蛋白(AFP)、γ-谷氨酰基转移酶(GGT)、铁蛋白(SF)在原发性肝癌诊断中的价值。方法 检测61例原发性肝癌患者、64例肝炎/肝硬化患者和55例健康对照组血清AFP、GGT、SF的含量。结果 AFP和SF检测的阳性率在原发性肝癌组与肝炎/肝硬化组比较差异具有统计学显著意义（P<0.05），肝癌组的阳性率高于肝炎/肝硬化组，GGT检测的阳性率在两组比较差异无统计学意义（P>0.05）；AFP、GGT和SF三项联合检测原发性肝癌的阳性率可提高到96.7%，与单项检测比较差异均具有统计学显著意义(P<0.05)。结论 血清AFP、GGT、SF联合检测可明显提高对原发性肝癌的阳性检出率。 |
| 关键词: 原发性肝癌 甲胎蛋白 γ-谷氨酰基转移酶 铁蛋白 |
| DOI：10.3969/j.issn.1674-3806.2009.12.21 |
| 分类号:R 735.7 |
| 基金项目: |
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| Clinical value of tumor marker alphafetoprotein (AFP), γ-glutamyle transpeptidase (GGT) and serum ferritin (SF) in the diagnosis of primary hepatocellular carcinoma (PHC) |
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XIONG Biao, CHEN Zhi-ping
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Laboratory Department, Qinzhou First Peoples′ Hospital, Guangxi 535000, China
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| Abstract: |
| ［Abstract］ Objective To investigate the clinical value of tumor marker alphafetoprotein (AFP), γ-glutamyle transpeptidase(GGT) and serum ferritin(SF) in the diagnosis of PHC. Methods AFP, GGT, SF in the serum were studied in 61 patients with PHC, 64 with hepatitis or LC, and 55 healthy individuals.Results The positive detection rate of AFP and SF in PHC were significantly higher than that in the hepatitis or LC（P<0.05）, but there was no statistically significant difference between the two groups in GGT（P>0.05）.Combined assay of AFP, GGT and SF will increase the detecting rate up to 96.7%, higher than any single marker examination respectively （P<0.05）. Conclusion The combining AFP, GGT and SF examination are superior to any single marker examination and can greatly increase the detecting rate of PHC. |
| Key words: Primary hepatocellular carcinoma Alphafetoprotein γ-glutamyle transpeptidase Serum ferritin |
