引用本文:孙志扬,唐伦先,徐 涛,陶妙娣,王 瑛,杨 成,张燕飞,魏 亮.重型颅脑损伤并发中枢性低钠血症67例诊治分析[J].中国临床新医学,2010,3(4):327-329.
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重型颅脑损伤并发中枢性低钠血症67例诊治分析
孙志扬,唐伦先,徐 涛,陶妙娣,王 瑛,杨 成,张燕飞,魏 亮
200120 上海,同济大学附属东方医院神经外科
摘要:
[摘要] 目的 探讨重型颅脑损伤后中枢性低钠血症的发病机制、诊断及治疗方法。方法 对67例中枢性低钠血症患者的临床表现、实验室检查、治疗方法及疗效进行回顾性分析。结果 重型颅脑损伤后发生中枢性低钠血症有两种因素:(1)抗利尿激素不适当分泌引起的综合征(SIADH),主要行限水治疗;(2)脑性盐耗引起的综合征(CSWS),主要给予补充盐水治疗。本组病例上述二种治疗后,全部患者低钠血症均得到纠正。结论 引起中枢性低钠血症有两种不同原因,且治疗方法也不同。
关键词:  中枢性低钠血症  重型颅脑损伤  治疗
DOI:10.3969/j.issn.1674-3806.2010.04.10
分类号:R 651.1
基金项目:
Analysis on diagnosis and treatment of 67 cases with central hyponatremia after severe brain injury
SUN Zhi-yang, TANG Lun-xian, Xu Tao, et al.
Department of Neurosurgery, East Hospital Affiliated of Tongji University, Shanghai 200120, China
Abstract:
[Abstract] Objective To explore the pathogenesis, diagnosis and treatment of centeral hyponatremia after severe brain injury.Methods The data of 67 patients with central hyponatremia were analyzed retrospectively on clinical manifestations, laboratory examination, treatment and efficacy.Results The patients of inappropriate secretion of antidiuretic hormone syndrome(SIADH) were treated with limited water intake and the patients of cerebral salt wasting syndrome(CSWS) with added salt. All patients with hyponatremia were corrected.Conclusion There are two forms of central hyponatremia after severe brain injury: Inappropriate SIADH and CSWS. Therefore, there are two different therapeutic methods for centeral hyponatremia after severe brain injury.
Key words:  Central hyponatremia  Severe brain injury  Cure