| 摘要: |
| ［摘要］ 目的 探讨液基薄层细胞学检测（TCT）联合阴道镜下宫颈活检在宫颈病变中的临床应用价值。方法 选择近年来在本院接受宫颈病变筛查的患者1 685例，所有患者均行TCT检测，细胞学分类采用TBS分类标准，对其中128例TCT检查阳性者行阴道镜下多点活检。 结果 细胞学异常阳性检出率为7.60%（128/1 685），其中不典型鳞状上皮细胞（ASCUS）56例（3.32%），低度鳞状上皮内瘤变（LSIU）42例（2.49%），高度鳞状上皮内瘤变（HSIU）26例（1.54%），宫颈鳞癌（SCC）3例（0.18%），宫颈腺癌（ACC）1例（0.06%）。阴道镜下病理诊断慢性炎症48例，轻度不典型增生（CINⅠ）41例，中度不典型增生（CINⅡ）17例，重度不典型增生及原位癌（CINⅢ）18例，宫颈鳞癌3例，宫颈腺癌1例。 结论 TCT检查应用于宫颈病变的筛查，明显提高了宫颈病变的阳性检出率，联合阴道镜检查及镜下活检，能提高宫颈病变的诊断率，及时发现宫颈早期病变及癌变。 |
| 关键词: 液基薄层细胞学 阴道镜 宫颈病变 |
| DOI：10.3969/j.issn.1674-3806.2010.04.14 |
| 分类号:R 446.63 |
| 基金项目: |
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| The application value of thin-layer liquid-based cytology combined with colposcopy in cervical lesions |
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YU Shan-zhi,MA gang,WU Ji-fang
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Department of Gynecology and Obstetrics, the People′s Hospital of Guangxi Zhuang Autonomous Region，Nanning 530021，China
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| Abstract: |
| ［Abstract］ Objective To investigate the clinical value of thin-layer liquid-based cytology (TCT) combined with colposcopy cervical biopsy in cervical lesions.Methods Choosing 1 685 cases received screening of cervical lesions in our hospital in recent years，all patients underwent TCT testing，cytology was classified using TBS classification criteria， of them 128 cases with TCT positive line were checked multiple biopsy under colposcopy.Results The rate of abnormal cytology-positive detection was 7.60% (128/1 685)，in which atypical squamous cells (ASCUS)，56 cases (3.32%)；low-grade squamous intraepithelial neoplasia (LSIU)，42 cases (2.49% )；high-grade squamous intraepithelial neoplasia (HSIU)，26 cases (1.54%)；cervical squamous cell carcinoma (SCC)，3 cases (0.18%)； cervical adenocarcinoma (ACC)，1 cases (0.06%). Colposcopy pathological diagnosis showed chronic inflammation in 48 cases, mild dysplasia (CINⅠ) in 41 cases，moderate dysplasia (CINⅡ) in 17 cases, severe dysplasia and carcinoma in situ (CINⅢ) in 18 cases ，cervical squamous cell carcinoma in 3 cases，cervical adenocarcinoma in 1 case.Conclusion Using TCT in the screening of cervical lesions can significantly increase the positive rate，the joint of colposcopy and endoscopic biopsy can improve the diagnosis rate of cervical lesions，and detect early cervical lesions and cancer. |
| Key words: Thin-layer liquid-based cytology(TCT) Colposcopy Cervical lesions |
