| 摘要: |
| ［摘要］ 目的 探讨尿酸、胆红素浓度与2型糖尿病的关系。方法 采用全自动生化分析仪，检测并比较65例2型糖尿病患者（其中血管病变患者32例）和57例健康者（对照组）血清总胆红素、直接及间接胆红素浓度和UA水平。结果 T2DM患者血清总胆红素（TBIL）、直接及间接胆红素含量明显低于对照组（P<0.05）,血清UA含量显著高于对照组(P<0.05)。血管病变的患者中血清TBIL<10 μmol/L的例数高于对照组（χ2=13.2，P<0.01），尿酸≥430 μmol/L的例数高于对照组(χ2=32.6，P<0.01)。结论 检测T2DM患者血清TBIL和UA水平对预测评估病情及预后T2DM有一定临床价值。 |
| 关键词: 2型糖尿病 胆红素 尿酸 |
| DOI：10.3969/j.issn.1674-3806.2010.04.24 |
| 分类号:R 587.1 |
| 基金项目: |
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| The clinical significance of the determination of serum uric acid and bilirubin in patients with type 2 diabetes mellitus |
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LIU Hua-xiang, LIN Yan
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Xieqiao Hospital, Huainan Dongfang Hospital Group, Fuyang Anhui 236221, China
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| Abstract: |
| ［Abstract］ Objective To study the relationship between the levels of serum uric acid and bilirubin and type 2 diabetes mellitus （T2DM）.Methods Sixty-five cases with T2DM（32 cases with angiopathy） and 57 healthy persons（control group）were randomly chosen for observation and comparison of the levels of serum uric acid, total bilirubin, direct and indirect bilirubin.Results The levels of serum uric acid in the T2DM group were significantly higher than that in the control group(P<0.05),however the levels of total bilirubin,direct and indirect bilirubin were significantly lower than that in the control group(P<0.05). The cases with level of total bilirubin lower than 10 μmol/L in the cases with angiopathy were more than the control group（χ2=13.2，P<0.01）. The cases with level of serum uric acid higher than 430 μmol/L were more than the control group(χ2=32.6，P<0.01).Conclusion The determinations of the levels of uric acid and bilinbin have some clinical significance in the prediction and evaluation for T2DM. |
| Key words: Type 2 diabetes mellitus Bilirubin Uric acid |
