| 摘要: |
| ［摘要］ 目的 探讨国产药物支架(DES)对急性ST段抬高型心肌梗死(STEMI)预后的影响。方法 对2004-03～2009-04共216例确诊为STEMI的患者分为两组，药物支架(DES)组（n=117）和裸支架（BMS）组（n=99），术后长期随访，观察术后12个月随访终点时支架内再狭窄发生率（ISR）及主要心血管不良事件（包括死亡、急性心肌梗死、靶血管再成形等）发生率。结果 216例患者经皮冠状动脉介入（PCI）治疗均成功。介入治疗3～12个月后随访结果显示,DES组再狭窄率明显低于BMS组（P<0.05），两组心血管不良事件发生率差异无统计学意义（P>0.05）。结论 DES在STEMI患者中有较好的安全性及临床疗效，再狭窄率明显低于BMS（P<0.05）。 |
| 关键词: 药物支架 急性ST段抬高型心肌梗死 再狭窄 心血管事件 |
| DOI：10.3969/j.issn.1674-3806.2010.12.30 |
| 分类号:R 542.2 |
| 基金项目: |
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| Safety and effectiveness of firebird drug eluting stent in acute ST-segment elevation myocardial infarction |
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LIU Ling, LIN Ying-zhong, WU Guang-wei,et al.
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Department of Cardiology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To evaluate the safety and effectiveness of firebird drug eluting stent (DES) in acute ST-segment elevation myocardial infarction. Methods 216 patients with acute ST-segment elevation myocardial infarction from March 2004 to April 2009 were divided into two groups: DES group(n=117) and BMS group(n=99). The occurrence rate of in-stent restenosis(ISR) and major adverse cardiovascular event (sudden death, reinfarction, revascularization) were analyzed after 12 months of implantation. Results Both groups showed a success rate of 100% in stenting. DES group was much better than BMS group in aspect of ISR（P<0.05）. There were no statistic difference in aspect of major adverse cardiovascular event (P>0.05) after 3 to 12 months of implantation. Conclusion DES implanted in patients with acute ST-segment elevation myocardial infarction is safety and effectiveness, DES is much better than BMS in aspect of ISR（P<0.05）. |
| Key words: Drug-eluting stent Acute ST-segment elevation myocardial infarction In-stent restenosis Major adverse cardiovascular event |
