引用本文:陈卫民,王 奇,刘 媛.小主动脉瓣环患者应用ATS.AP瓣置换20例效果分析[J].中国临床新医学,2010,3(12):1235-1237.
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小主动脉瓣环患者应用ATS.AP瓣置换20例效果分析
陈卫民,王 奇,刘 媛
545005 广西,柳州市工人医院心胸外科
摘要:
[摘要] 目的 观察小主动脉瓣环患者置入ATS.AP瓣是否存在置入瓣膜与患者不匹配(Prosthesis-Patient Mismatch,PPM)现象。 方法 选择2008-01~2010-03间20例主动脉瓣环径≤20 mm行ATS.AP瓣置换患者(小瓣环组)及20例非小主动脉瓣环行常规机械瓣置换患者(正常瓣环组),用彩色多普勒超声仪对患者左心功能进行术前、术后监测,比较其术前、术后左心功能指标的变化,比较术前术后主动脉瓣跨瓣峰值压差、主动脉EOA指数,观察有无发生机械瓣与体表面积不相匹配现象(PPM)。结果 小瓣环组术后左室重量指数、主动脉跨瓣峰值压差、左室后壁厚度较术前显著降低(P<0.01);左心室射血分数、主动脉瓣EOA指数显著增高(P<0.01)。两组术后比较仅主动脉跨瓣峰值差异有统计学意义(P<0.01),其余各项指标比较差异均无统计学意义(P>0.05)。结论 小主动脉瓣环患者置换ATS.AP瓣后无置入瓣膜与患者不匹配现象,左心功能指标接近或达到正常瓣环瓣膜置换者。
关键词:  小主动脉瓣环  瓣膜置换  效果分析
DOI:10.3969/j.issn.1674-3806.2010.12.32
分类号:R 654.2
基金项目:
Effect analysis of ATS.AP valve replacement in 20 patients with small aortic root
CHEN Wei-min, WANG Qi, LIU Yuan
Department of Cardiothoracic Surgery,Liuzhou Worker′s Hospital,Guangxi 545005, China
Abstract:
[Abstract] Objective To study whether prosthesis-patient mismatch (PPM) would exist in patients with small aortic root treated with ATS.AP replacement. Methods Twenty patients with small aortic root (< 20 mm in diameter) receiving ATS.AP valve replacement (experimental group) and 20 patients with normal size root receiving mechanical valves replacement (control group)were selected. All of them were admitted from January 2008 to March 2010 to our hospital. Various data on left ventricular function before and after operation were obtained by color Doppler ultrasound and compared.Results After operation in experimental group there was a significant reduction in left ventricular mass index pressure gradient,peak pressure gradients across aortic value, and left ventricular posterior wall thickness (all P<0.01),and a significant increase in left ventricular ejection fraction and EOA index of aortic valve (all P<0.01).After operation there was a significant difference in peak pressure gradients across aortic valve (P<0.01) and no significant difference in other indexes (all P>0.05) between two groups.Conclusion Patients with aortic root treated with ATS.AP replacement have no prosthesis-patient mismatch.Left heart function of ATS.AP replacement is close to or the same as that of normal mechanical valves replacement.
Key words:  Small aortic root  Valve replacement  Effect analysis