| 摘要: |
| ［摘要］ maspin是一种肿瘤抑制基因，该基因具有诱导肿瘤细胞凋亡，抑制肿瘤细胞运动、侵袭、转移和肿瘤新生血管生成等作用。maspin基因表达受体内多条途径的精确调控，但其在肝癌中作用的研究较少。该文就maspin基因的抑癌作用机制及其在肝癌中作用的研究进展作一综述。 |
| 关键词: maspin基因 抑癌作用 肝癌 |
| DOI：10.3969/j.issn.1674-3806.2012.02.33 |
| 分类号:R 735.3 |
| 基金项目:南宁市科学研究与技术开发计划课题（编号：zc2010004c） |
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| Progress on maspin gene in tumor suppression and liver cancer |
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LIU Jin-xin,TAN Yi
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Department of General Surgery, the First People′s Hospital of Nanning,Guangxi 530022, China
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| Abstract: |
| ［Abstract］ maspin is a tumor suppressive gene and plays an important role in promoting tumor cells apoptosis, suppressing tumor cells mobility, invasive, metastasis and angiogenesis. The expression of maspin gene is precisely controlled by several pathways. But the role of maspin in liver cancer is poorly investigated.In the paper,the progress on the mechanisim of tumor suppression of maspin gene and its role in liver cancer were reviewed. |
| Key words: maspin gene Tumor suppression Liver cancer |
