| 摘要: |
| ［摘要］ 目的 评价Apnealink睡眠初筛监测仪对中国南方人阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的诊断价值。方法 53例受试者第一晚先用Embla S7000多导睡眠分析仪行整夜多导睡眠图(PSG)监测，第二晚再用Apnealink初筛仪行整夜睡眠初筛监测。评价Apnealink的灵敏度、特异度、假阴性率(FNR)、假阳性率（FPR)及一致率（kappa值）等指标，以PSG-AHI为诊断OSAHS的金标准,以Apnealink-AHI绘制受试者工作特征曲线(ROC曲线),寻找Apnealink的最佳诊断点。结果 Apnealink以AHI=5次/h为诊断值筛查OSAHS的灵敏度为87.9%，特异度为95.0%，FNR为12.1%，FPR为5.0%，一致率（kappa值）为0.805（P=0.000）。以PSG-AHI=5作为诊断OSAHS的金标准,绘制ROC曲线,得出Apnealink对OSAHS的最佳诊断值为AHI=5.0次/h，其对应的灵敏度为87.9%,特异度为95.0%，曲线下面积为0.977；95%可信区间为0.946～1.007，P=0.000。结论 应用Apnealink监测仪对OSAHS的诊断准确性高,临床应用价值大，建议使用AHI≥5次/h为阳性诊断值。 |
| 关键词: 阻塞性睡眠呼吸暂停低通气综合征 睡眠初筛仪 诊断试验 ROC曲线 |
| DOI：10.3969/j.issn.1674-3806.2013.02.03 |
| 分类号:R 563 |
| 基金项目:广西自然科学基金资助项目(编号：桂科自0991211；桂科自0991217) |
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| Validation of a portable sleep monitor (Apnealink) for identifying patients with suspected obstructive sleep apnea-hypopnea syndrome |
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JIANG Li-jun, LIN Ying-zhong, LIU Jian-hong,et al.
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Sleep Disordered and Breathing Center of Guangxi, the People ’s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To validate the portable recording device（Apnealink） for use as a screening tool for obstructive sleep apnea-hypopnea syndrome in clinical practice in the south of china.Methods We compared the AHI obtained from the Apnealink device during a study in the subjects’ homes or in the laboratory to that obtained during attended sleep-laboratory polysomnography to assess the sensitivity，specificity，false positive rate，false negative rate and kappa value of the device in consecutive subjects. The portable sleep monitor study was was performed in the next day of the sleep-laboratory polysomnography study. Using receiver operating characteristic (ROC) curve,we obtained the best cut-off point of Apnealink.Results When obstructive sleep apnea-hypopnea syndrome was diagnosed on a cut-off of an AHI value of 5 events per hour, the Apnealink device had a sensitivity of 87.9%, a specificity of 95.0%,a false negative rate of 12.1%,a false positive rate of 5.0% and a kappa value of 0.805（P=0.000）. Using ROC curve,we obtained a best cut-off point of Apnealink of AHI value of 5 events per hour(sensitivity 87.9%,specificity 95%).The area under the curve (AUC) of ROC curve was 97.7%(95% confidence interval 0.946 to 1.007,P=0.000).Conclusion This study demonstrates that the Apnealink device is highly sensitive and specific in calculating AHI,and is useful in the diagnosis of OSHAS. It is suggested to use a AHI value of 5 events per hour as a best cut-off point of Apnealink. |
| Key words: Obstructive sleep apnea-hypopnea syndrome Portable sleep monitor Diagnostic test ROC curve |
