引用本文:娄唯鸣(综述),谭 毅(审校).他汀类药物在急性冠状动脉综合征中抗炎作用的研究进展[J].中国临床新医学,2013,6(4):380-384.
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他汀类药物在急性冠状动脉综合征中抗炎作用的研究进展
娄唯鸣(综述),谭 毅(审校)
457001 河南,濮阳市油田总医院心内科
摘要:
[摘要] 急性冠状动脉综合征(ACS)是常见的冠状动脉粥样硬化性心脏病的急症,炎症在动脉粥样硬化过程中起重要作用。3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂他汀类药物现已广泛应用于冠心病的一级、二级预防,越来越多的证据显示他汀类药物具有显著抗炎作用。该文对他汀类药物在ACS中的抗炎作用作一简要的综述。
关键词:  他汀类药物  急性冠状动脉综合征  动脉粥样硬化  抗炎作用
DOI:10.3969/j.issn.1674-3806.2013.04.35
分类号:R 54
基金项目:
Research progress on the anti-inflammatory effects of statins in acute coronary syndromes
LOU Wei-ming,TAN Yi
Department of Cardiovascular Disease,the General Hospital of Oilfield of Puyang, Henan 457001, China
Abstract:
[Abstract] Acute coronary syndromes(ACS) are a common emergency of coronary heart disease, inflammation plays a key role in atherosclerosis.3-hydroxy-3-methylglutary coenzyme A reductase inhibits statins has been widely used in the primary and secondary prevention of coronary heart disease.Accumulating evidence has revealed that statins have a significant anti-inflammatory effect.This paper briefly reviewed the research progress on the anti-inflammatory mechanism of statins in ACS.
Key words:  Statins  Acute coronary syndromes(ACS)  Atherosclerosis  Anti-inflammatory effect