摘要: |
[摘要] 急性冠状动脉综合征(ACS)是常见的冠状动脉粥样硬化性心脏病的急症,炎症在动脉粥样硬化过程中起重要作用。3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂他汀类药物现已广泛应用于冠心病的一级、二级预防,越来越多的证据显示他汀类药物具有显著抗炎作用。该文对他汀类药物在ACS中的抗炎作用作一简要的综述。 |
关键词: 他汀类药物 急性冠状动脉综合征 动脉粥样硬化 抗炎作用 |
DOI:10.3969/j.issn.1674-3806.2013.04.35 |
分类号:R 54 |
基金项目: |
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Research progress on the anti-inflammatory effects of statins in acute coronary syndromes |
LOU Wei-ming,TAN Yi
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Department of Cardiovascular Disease,the General Hospital of Oilfield of Puyang, Henan 457001, China
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Abstract: |
[Abstract] Acute coronary syndromes(ACS) are a common emergency of coronary heart disease, inflammation plays a key role in atherosclerosis.3-hydroxy-3-methylglutary coenzyme A reductase inhibits statins has been widely used in the primary and secondary prevention of coronary heart disease.Accumulating evidence has revealed that statins have a significant anti-inflammatory effect.This paper briefly reviewed the research progress on the anti-inflammatory mechanism of statins in ACS. |
Key words: Statins Acute coronary syndromes(ACS) Atherosclerosis Anti-inflammatory effect |