| 摘要: |
| ［摘要］ 目的 观察急性呼吸窘迫综合征（ARDS）患者入院血清白蛋白和前白蛋白与死亡预后的关系，探讨其能否作为死亡预后的指标。方法 回顾性分析住院ARDS患者50例临床资料，了解不同血清白蛋白和前白蛋白水平对病死率的影响，并进行多因素Logistic回归分析，筛选死亡预后的风险因素。结果 死亡28例，存活22例。死亡组患者的血清白蛋白、前白蛋白水平低于存活组（P<0.05），肺损伤积分大于存活组（P<0.05）。低前白蛋白组病死率高于前白蛋白正常或升高组；低白蛋白组病死率高于正常白蛋白组（P<0.05）。慢性阻塞性肺疾病（COPD）史、糖尿病史，白蛋白、前白蛋白及肺损伤积分是ARDS患者死亡预后的危险因素，白蛋白与前白蛋白的OR值分别为2.543和3.008。结论 白蛋白与前白蛋白可用于预测ARDS患者的死亡预后。 |
| 关键词: 白蛋白 前白蛋白 急性呼吸窘迫综合征（ARDS） 预后评估 |
| DOI：10.3969/j.issn.1674-3806.2013.10.13 |
| 分类号:R 563.8 |
| 基金项目: |
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| Evaluation of the prognosis of acute respiratory distress syndrome patients by serum albumin and prealbumin |
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ZHANG Yi
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Department of Respiratory, the 416 Hospital of Nuclear Industry，Sichuan 610050,China
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| Abstract: |
| ［Abstract］ Objective To probe whether serum albumin and prealbumin can be used as a prognostic indicator of death by observing the relationship between serum albumin, prealbumin and death in hospitalized patients with acute respiratory distress syndrome(ARDS).Methods The clinical data of 50 cases of hospitalized patients with ARDS were retrospectively analyzed, the influence on mortality of different serum albumin and prealbumin levels was studyed, multi-factor Logistic regression analysis was carried on to pick out prognostic risk factors for death.Results Twenty-eight patients died and 22 survived, the serum albumin and prealbumin levels of the die group was lower than that of the survival group(P<0.05), the lung injury scores was higher than that of the survival group(P<0.05). The fatality rate of the low prealbumin group was higher than that of the normal or elevated prealbumin group; the fatality rate of lower albumin group was higher than that of the normal albumin group(P<0.05). COPD history, diabetes history, albumin, prealbumin level and lung injury score were risk factors for prognosis of ARDS death, the OR values of albumin and prealbumin were 2.543 and 3.008 respectively.Conclusion Albumin and prealbumin could be used to predict the death prognosis of ARDS patients. |
| Key words: Albumin Prealbumin Acute respiratory distress syndrome(ARDS) Prognosis evaluation |
