摘要: |
[摘要] 目的 探讨B型尿钠肽(BNP)检测对慢性心肾综合征患者诊断和治疗的临床意义。方法 对该院以心脏疾病为基础病的慢性心力衰竭患者54例的临床资料进行回顾性分析,并按照患者入院时血肌肝(Scr)是否≥133 mmol/L分为单纯慢性心力衰竭组26例和慢性心肾综合征组28例。结果 慢性心肾综合征组的BNP的水平[(1321.5±93.88)pg/L]明显高于单纯慢性心力衰竭组[(865.4±120.32)pg/L](P<0.05)。两组患者的BNP水平均与左室舒张末期内径(LVEDD)呈正相关,与左室射血分数(LVEF)呈负相关(P<0.05)。结论 BNP检测对慢性心肾综合征患者心功能的诊断、病情的判断、指导治疗以及评估预后有重要意义。 |
关键词: B型尿钠肽(BNP) 心肾综合征 慢性心力衰竭 |
DOI:10.3969/j.issn.1674-3806.2013.10.18 |
分类号:R 542.2 |
基金项目: |
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Clinic significance of BNP testing in diagnosis and treatment of patients with chronic cardio-renal syndrome |
YIN Rui
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Department of Cardiology, the 416 Hospital of Nuclear Industry,Chengdu 610050,China
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Abstract: |
[Abstract] Objective To understand the clinical significance of BNP in patients with chronic cardio-renal syndrome.Methods The clinical data of 54 chronic heart failure patients with heart disease as underlying disease in the 416 Hospital of Nuclear Industry was retrospectively analyzed.Twenty-six hospitalized patients with simple chronic heart failure(simple heart failure group), and 28 hospitalized patients with chronic cardio-renal syndrome(cardio-renal syndrome group) were retrospectively analyzed.Results The BNP level of chronic cardio-renal syndrome group was significantly higher than that of simple heart failure group[(1321.5± 93.88) vs (865.4 ±120.32)pg/L, P<0.05); The BNP levels of two groups were positively related to the LVEDD and negative related to LVEF(P<0.05).Conclusion BNP can be as applied to cardiac function diagnosis, severity evaluation, therapy guide and prognosis evaluation in patients with chronic cardio-renal syndrome. |
Key words: Brain natriuretic peptide Cardio-renal syndrome Chronic heart failure |