| 摘要: |
| ［摘要］ 目的 比较胸部肿瘤调强放射治疗（IMRT）与常规放射治疗（CRT）剂量-体积直方图（DVH）参数及动态心电图（DCG）的改变情况。方法 选择72例胸部肿瘤患者，根据治疗方案分为IMRT组和CRT组，每组36例，分别于治疗前、中、后进行24 h DCG监测，分析两组DVH参数及DCG改变情况。结果 IMRT组心脏V30、V40、V50均明显低于CRT组，差异有统计学意义（P<0.01），IMRT组及CRT组治疗前、中、后DCG异常发生率比较，差异有统计学意义（P<0.01），治疗中、后IMRT组DCG异常发生率均低于CRT组，差异有统计学意义（P<0.05）。结论 两种治疗方法均可引起DCG改变，但在相同剂量照射时，IMRT组心脏受照体积减少，对DCG影响更小。 |
| 关键词: 胸部肿瘤 调强放射治疗 常规放射治疗 DVH图 动态心电图 |
| DOI：10.3969/j.issn.1674-3806.2014.03.02 |
| 分类号:R 730；R 540.4+1 |
| 基金项目:广西自然科学基金资助项目(编号：桂科自0832207)；广西卫生厅重点科研课题（编号：桂卫重2012103）；南宁市青秀区科学研究与技术开发课题（编号：2012S04） |
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| Comparison of dose volume histogram parameters and dynamic electrocardiogram changes between intensity modulated radiation therapy and conventional radiotherapy for the thoracic tumor |
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YANG Su-ping, QIN Xiao-bo, HAO Yan-rong, et al.
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Department of Electrocardiogram, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To compare the dose volume histogram(DVH) parameters and dynamic electrocardiogram(DCG) changes between intensity modulated radiotherapy(IMRT) and conventional radiotherapy(CRT) for the thoracic tumor.Methods The patients with thoracic tumors were divided into IMRT group and CRT group,with 36 cases in every group, two groups were tested with 24-hour DCG before, during and after treatment to compare DVH parameters and DCG changed.Results Heart V30-V50 in IMRT group were significantly lower than that in the CRT group, with statistical significance（P<0.01）, the abnormity incidence rates of DCG was statistically significant between IMRT group and CRT group(before, during and after treatment)(P<0.01), the abnormity incidence rates of DCG were lower in IMRT group than that of CRT group during and after treatment, with statistical significance（P<0.05）.Conclusion Both treatments can cause DCG change, but at the same dose IMRT group has smaller heart irradiation volume and lighter change of DCG. |
| Key words: Thoracic tumor Intensity modulated radiation therapy Conventional radiotherapy Dose volume histogram Dynamic electrocardiogram |
