| 摘要: |
| ［摘要］ 目的 研究右侧星状神经节阻滞（SGB）对大鼠体外循环（CPB）转流期间微循环变化的影响。方法 选用20只SD大鼠随机分为体外循环组（C组）10只，右侧行星状神经节阻滞+体外循环组（RC组）10只。两组转体循环后转流1 h。在转流前，定于动脉静脉置管成功后为T0;体外循环转流开始后30 min为T1;体外循环后1 h为T2。3个时间点观察两组大鼠的血压、心率、血气及乳酸含量,计算动静脉血氧分压差(Pa-vO2)。结果 两组大鼠乳酸、Pa-vO2和血压不同时间点差异有统计学意义（P<0.05）；两组心率、乳酸和Pa-vO2的组间和分组间有交互作用（P<0.05）；两组心率和乳酸的组间差异有统计学意义（P<0.05）。结论 SGB能改善大鼠体外循环后的灌注，可提高机体的摄氧能力，改善机体的微循环。 |
| 关键词: 微循环 体外循环 星状神经节阻滞 大鼠 |
| DOI：10.3969/j.issn.1674-3806.2014.05.02 |
| 分类号:R 614.4 |
| 基金项目:广西自然科学基金资助项目（编号：2012GXNSFAA053111） |
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| The effects of right stellate ganglion block on rat microcirculation during extracorporeal circulation |
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HUANG Qian，ZHANG Bing-dong，WANG Ling
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Department of Anesthesiology and Cardiovascular Institute, the First Affiliated Hospital of Guangxi Medical University， Nanning 530021，China
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| Abstract: |
| ［Abstract］ Objective To observe the effects of right stellate ganglion block(SGB) on rat microcirculation during extracorporeal circulation.Methods Twenty healthy SD rats were selected and randomly divided into two groups：control group（C group）and SGB group(RC group). Both C group and RC group were processed by extracorporeal circulation for 1 h.RC group received stellate ganglion block with bupivacaine before Undergoing cardiopulmonary bypass.The observation points included T0:before extracorporeal circulation；T1: after 30 min of extracorporeal circulation；T2: after 1 h of extracorporeal circulation.The observation included blood pressure, heart rate,blood gas parameters difference of oxygen pressure between artery and vein(Pa-vO2) and blood lactate.Results There were significant difference in lactate, Pa-vO2 and blood pressure at different time between two groups(P<0.05). There was an interavtion effect in heart rate, lactate and Pa-vO2 between treatment and time（P<0.05）. There were significant difference in the lactate and heart rate between two groups(P<0.05).Conclusion Right stellate ganglion block can improve the tissue perfusion by ameliorating rat microcirculation during extracorporeal circulation. |
| Key words: Microcirculation Extracorporeal circulation Stellate ganglion block Rat |
