引用本文:洪 雁,梁 智,方 芳,刘 英,黄文越,苏 宇.事件相关电位P300对早期血管性痴呆的诊断价值[J].中国临床新医学,2014,7(5):410-413.
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事件相关电位P300对早期血管性痴呆的诊断价值
洪 雁,梁 智,方 芳,刘 英,黄文越,苏 宇
530022 广西,南宁市第一人民医院神经内科
摘要:
[摘要] 目的 探讨事件相关电位P300对早期血管性痴呆的诊断价值。方法 选择50例血管性痴呆患者(血管性痴呆组)、49例动脉硬化症无痴呆患者(动脉粥样硬化组)和48名健康人(健康人组)分别进行P300检查,比较三组的检查结果。结果 血管性痴呆组P300潜伏期较动脉粥样硬化组、健康人组明显延长,波幅降低,差异有统计学意义(P<0.01)。结论 事件相关电位P300检测在血管性痴呆早期诊断中具有较高的应用价值。
关键词:  事件相关电位P300  血管性痴呆  诊断
DOI:10.3969/j.issn.1674-3806.2014.05.08
分类号:R 74
基金项目:广西南宁市科学研究与技术开发计划项目(编号:ZC20123002)
The value of event related potential P300 in early diagnosis of vascular dementia
HONG Yan, LIANG Zhi, FANG Fang, et al.
Department of Neurology, the First People′s Hospital of Nanning, Guangxi 530022, China
Abstract:
[Abstract] Objective To explore the value of event related potential P300 in early diagnosis of vascular dementia.Methods Inspection of P300 was performed between 50 cases of patients with vascular dementia(group of dementia), 49 arteriosclerosis patients without dementia(group of arteriosclerosis) and 48 healthy people(group of healthy people).Results The P300 incubation period of the group of dementia was prolonged significantly and amplitude decreased compared with the group of arteriosclerosis and the group of healthy people. The difference was statistically significant between the compared groups(P<0. 01).Conclusion Event related potential checking has higher application value in early diagnosis of vascular dementia.
Key words:  Event related potential P300  Vascular dementia  Diagnosis