| 摘要: |
| ［摘要］ 目的 探讨有创-无创序贯机械通气治疗慢性阻塞性肺疾病急性加重期（AECOPD）合并Ⅱ型呼吸衰竭的临床疗效。方法 随机选取AECOPD合并Ⅱ型呼吸衰竭患者64例，按照就诊先后顺序半随机分为治疗组（32例）和对照组（32例），在常规治疗基础上，治疗组采用无创序贯通气治疗，对照组采用常规有创通气治疗，观察两组主要通气指标变化情况。结果 治疗组总通气时间少于对照组（P<0.05），呼吸机相关性肺炎（VAP）发生率低于对照组（P<0.05）。结论 有创-无创序贯性机械通气治疗AECOPD合并Ⅱ型呼吸衰竭临床疗效显著，缩短通气时间，降低VAP发生率，具有良好的临床应用价值，值得推广。 |
| 关键词: 慢性阻塞性肺疾病急性加重期 有创-无创序贯机械通气 Ⅱ型呼吸衰竭 |
| DOI：10.3969/j.issn.1674-3806.2014.05.17 |
| 分类号:R 56 |
| 基金项目: |
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| Clinical effect of sequential invasive and non-invasive mechanical ventilation in treatment of AECOPD combined with type Ⅱ respiratory failure |
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CHEN Zhan-wei
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Department of Respiratory Medicine, the People′s Hospital of Tangyin County, Henan 456150,China
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| Abstract: |
| ［Abstract］ Objective To observe the clinical effect of sequential invasive and non-invasive mechanical ventilation in treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD) combined with type Ⅱ respiratory failure.Methods Sixty-four patients with AECOPD combined with type Ⅱ respiratory failure in our hospital were randomly selected and divided into two groups. On the basis of routine treatment,32 patients in the treatment group were given sequential non-invasive ventilation and another 32 patients in the control group were given convention ventilation respectively. The main ventilation index were compared.Results Compared with the control group，the total ventilation time was significant shorter and the incidence of ventilator-associated pneumonia(VAP) was significant lower in the treatment group（P<0.05）.Conclusion The sequential invasive and non-invasive ventilation in treatment of AECOPD combined with type Ⅱ respiratory failure has better clinical effect, shortening the total ventilation time and reducing the incidence of VAP.It is of certain clinical value and is worth popularizing. |
| Key words: Acute exacerbation of chronic obstructive pulmonary disease（AECOPD） Sequential invasive and non-invasive mechanical ventilation Type Ⅱ respiratory failure |
