| 摘要: |
| ［摘要］ 目的 探讨甲亢合并周期性麻痹的临床特点，减少漏诊、误诊的发生。方法 回顾性分析26例甲亢合并周期性麻痹患者的临床资料。结果 患者经补钾后1～18 h病情迅速缓解，并予正规抗甲状腺药物治疗后22例甲功恢复正常，2例反复发作2次，经调整抗甲状腺药物后甲功恢复正常，2例因口服药出现不良反应改131I治疗甲功恢复正常。26例随访6个月～1年内无周期性麻痹复发。结论 甲亢合并周期性麻痹补钾治疗后症状迅速改善，积极有效控制甲亢是预防复发的关键，同时注意避免饱餐、感染、过度劳累、静脉输入高渗葡萄糖等诱发因素。 |
| 关键词: 甲亢 周期性麻痹 体会 |
| DOI：10.3969/j.issn.1674-3806.2014.08.16 |
| 分类号:R 582 |
| 基金项目: |
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| Clinical experience on diagnosis and treatment of 26 patients with hyperthyroidism complicated by periodic paralysis |
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JIANG Jia-jun
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Dapartment of Thyroid, Dandong Institute of Chronic Diseases, Liaoning 118000, China
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| Abstract: |
| ［Abstract］ Objective To investigate the clinical featurs of hyperthyroidism patients with periodic paralysis in order to dearease the rate of missed diagnosis and misdiagnosis.Methods A retrospective analysis of the clinical data was performed of 26 patients with hyperthyroidism complicated by periodic paralysis.Results Within 1to 18 h after potassium treatment, the patients′symptoms and signs quickly relieved, and after antithyroid drug treatment thyroid function returned to normal in 22 patients.Two patients experienced 2 times of recurrent attacks and their thyroid function returned to normal after adjusting antithyroid drug. Due to adverse reaction of oral drugs,2 patients were treated with 131I treatment instead of oral drugs and their thyroid function returned to normal after 131I treatment. Within 6 to 12 months of follow-up,no recurrence of periodic paralysis appeared in 26 patients.Conclusion For patients with hyperthyroidism complicated by periodic paralysis,potassium supplementation can rapidly improve their symptoms; active and effective antithyroid drugs treatment is key to preventing recurrence; at the same time, it is necessary to avoid the predisposing factors such as overeat ingestion, infection, excessive exertion, and intravenous infusion of hypertonic glucose and so on,in order to prevent recurrence. |
| Key words: Hyperthyroidism Periodic paralysis Experience |
