引用本文:祝兴年.卡托普利联合川芎嗪治疗急性肾小球肾炎的临床效果观察[J].中国临床新医学,2014,7(10):956-958.
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卡托普利联合川芎嗪治疗急性肾小球肾炎的临床效果观察
祝兴年
542499 广西,平乐县人民医院内二科
摘要:
[摘要] 目的 观察卡托普利联合川芎嗪治疗急性肾小球肾炎的临床效果。方法 选择80例急性肾小球肾炎患者为研究对象,随机分为观察组和对照组各40例。对照组给予常规治疗,观察组在常规治疗的基础上给予卡托普利联合川芎嗪治疗,比较两组的疗效。结果 观察组血尿转阴率为75.00%,明显高于对照组的45.00%,差异具有统计学意义(P<0.01);观察组肉眼血尿消退时间为(2.5±0.5)d,镜下血尿消退时间为(2.6±0.6)d,水肿消退时间为(3.7±0.4)d,血压恢复时间为(4.1±0.6)d,均明显短于对照组,差异具有统计学意义(P<0.01)。结论 在常规治疗基础上联合应用卡托普利与川芎嗪治疗急性肾小球肾炎能缩短疗程,提高疗效。
关键词:  卡托普利  川芎嗪  急性肾小球肾炎
DOI:10.3969/j.issn.1674-3806.2014.10.21
分类号:R 69
基金项目:
Clinical effects of captopril combined with ligustrazine in the treatment of acute glomerulonephritis
ZHU Xing-nian
The 2nd Department Internal Medicine, the People′s Hospital of Pingle County, Guangxi 542499, China
Abstract:
[Abstract] Objective To investigate clinical effect of captopril combined with ligustrazine in the treatment of acute glomerulonephritis.Methods Eighty patients with acute glomerulonephritis were divided into the control group(n=40) was treated by conventional therapy and the observation group(n=40) was treated by captopril combined with ligustrazine on the basis of control group. The clinical effect of two groups were compared.Results After treatment,the hematuria negative rate of the observation group(75.00%) was higher than that of the control group(45.00%)(P<0.01). Macroscopic hematuria subsided time was (2.5±0.5)d, microscopic hematuria subsided time was (2.6±0.6)d, edema subsided time was (3.7±0.4)d, blood pressure recovery time was (4.1±0.6)d in the observation group were significantly shorter than those in the control group(P<0.01).Conclusion Captopril combined with ligustrazine on the basis of conventional therapy in the treatment of acute glomerulonephritis can effectively shorten the course of treatment and improve efficacy.
Key words:  Captopril  Ligustrazine  Acute glomerulonephritis