| 摘要: |
| ［摘要］ 作为特发于老年期的原发性失眠，老年失眠症是困扰老年人的常见病症。阿尔茨海默病(AD)又称老年痴呆症，是一种神经退行性疾病，是痴呆病中最常见的类型。现有研究表明失眠症与认知功能障碍具有相关性。而轻度认知功能障碍（MCI）可能是痴呆的早期信号，是预防和治疗AD的关键阶段。鉴于MCI发病的隐匿性及其引发痴呆的危险性，早期识别MCI危险因素、早期诊断并进行有效的预防性干预具有重要临床意义。该文对老年人失眠与轻度认知功能改变之间关系的研究进展作一综述，以期为AD的早期防治提供新的研究思路。 |
| 关键词: 老年失眠症 轻度认知功能障碍 阿尔茨海默病 |
| DOI：10.3969/j.issn.1674-3806.2015.07.29 |
| 分类号:R 741 |
| 基金项目:广西崇左市科学研究与技术开发计划项目（编号：崇科攻1324005） |
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| Clinical research progress on the senile insomnia and mild cognitive impairment |
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ZHONG Liang, LIU Li, HE Rong-xin, et al.
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Department of Neurology, Guangxi Zhuang Autonomous Region National Hospital, Nanning 530001, China
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| Abstract: |
| ［Abstract］ As the primary insomnia with onset in old age, senile insomnia is a common disease in the elderly. Alzheimer′s disease(AD), the most common cause of dementia, is a kind of neurodegenerative disease. Recent studies have shown that the insomnia is associated with cognitive dysfunction, and the incidence of dementia in elderly patients with insomnia markedly increased. And, mild cognitive impairment(MCI) may be an early sign of dementia, and is the key stage of the prevention and treatment of AD. Given the occult onset of MCI and significantly higher risk of dementia, early identification of risk factors, early diagnosis and effective preventive intervention of MCI have important clinical significances. The purpose of this paper is to summarize the relationship between insomnia and cognitive function in the elderly, and to provide a new research idea for the early prevention and treatment of AD. |
| Key words: Senile insomnia Mild cognitive impairment Alzheimer′s disease |
