| 摘要: |
| ［摘要］ 目的 探讨三维超声汇聚征在乳腺肿块诊断及预后评估中的价值。方法 对165例乳腺肿块患者术前行三维超声检查，观察肿块冠状面汇聚征的表达情况，并与肿块直径、组织学分级、淋巴结状态以及雌激素受体(ER)、孕激素受体(PR)、人表皮生长因子-2(CerbB-2)及Ki-67结果作比较，统计分析汇聚征与上述指标间关系。结果 汇聚征诊断乳腺恶性肿块的灵敏度为67.7%，特异度为93.1%。汇聚征显示率在浸润性癌和非浸润性癌间差异有统计学意义(P<0.01)。汇聚征显示率与直径、组织学分级以及ER、PR表达有关。与无汇聚征组相比，有汇聚征组的肿块直径多≤2 cm(P<0.05)，组织学分级多为Ⅱ级(P<0.05)，且ER、PR的阳性率较高(P<0.05)。两组的淋巴结状态、CerbB-2及Ki-67表达之间差异无统计学意义(P>0.05)。结论 三维超声汇聚征表达情况有助于乳腺癌预后评估，从而为临床治疗方案的制定提供更多有效影像学信息。 |
| 关键词: 三维超声 乳腺肿块 汇聚征 预后 |
| DOI：10.3969/j.issn.1674-3806.2015.09.03 |
| 分类号:R 445.1 |
| 基金项目:广西医疗卫生重点科研课题（编号：重200813）；广西科学研究与技术开发计划项目（编号：桂科攻14124004-1-13） |
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| Value of retraction phenomenon at three-dimensional ultrasonography in diagnosis and prognosis evaluation in breast lesions |
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ZHANG Bing, WANG Xiao-yan, NONG Mei-fen, et al.
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Department of Ultrasound, the People′s Hospital of Guangxi Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To investigate the value of retraction phenomenon at three-dimensional ultrasonography(3D-US) in diagnosis and prognosis evaluation in breast lesions.Methods 165 patients with breast lesions who underwent 3D-US examination were included. The presence of the retraction phenomenon in the coronal plane was evaluated. Pathologic prognostic factors, including tumor size, histologic grade, lymph node status, estrogen receptor(ER), progesterone receptor(PR) status, human epidermal growth factor receptor 2(Cerb-B2) and Ki-67 expression were determined. The correlation of the retraction phenomenon and prognostic factors was analyzed.Results The sensitivity and specificity of retraction phenomenon in the diagnosis of breast cancers were 67.7% and 93.1% respectively. The detection rates of the retraction phenomenon in the invasive cancer and the non-invasive cancer were 80.3% and 11.8%(P<0.001). The retraction phenomenon was correlated to the tumor size, histologic grade, estrogen and progesterone receptor status. Compared with the breast cancer without the retraction phenomenon, the tumor size with the retraction phenomenon was more likely to show a smaller diameter less than 2 cm(P<0.05), a lower histologic grade with grade Ⅱ(P<0.05), and a higher positive rate of ER and PR(P<0.05). The lymph node status and the expression of the CerB-2 and Ki-67 in the two groups had no significant difference(P>0.05).Conclusion The retraction phenomenon of three-dimensional US may be useful in the diagnosis and prognosis evaluation in breast lesions. |
| Key words: Three-dimensional ultrasonography Breast lesions Retraction phenomenon Prognosis |
