| 摘要: |
| ［摘要］ 目的 探讨肺保护性通气治疗急性呼吸窘迫综合征（ARDS）的临床疗效。方法 将62例ARDS患者随机分为两组，其中对照组30例给予常规机械通气治疗，观察组32例给予肺保护性通气治疗，比较两组患者血氧分压（PaO2）、二氧化碳分压（PaCO2）、氧合指数（PaO2/FiO2）的变化情况以及带机时间、住院时间、呼吸机相关肺损伤（VALI）的发生率等。结果 观察组患者经通气后8 h、24 h、48 h的PaO2、PaCO2、PaO2/FiO2均明显高于对照组（P<0.05）,带机时间和住院时间均明显短于对照组（P<0.05），VALI发生率也明显低于对照组（P<0.05）。结论 肺保护性通气能明显改善氧合，缩短带机时间和住院时间，减少VALI发生，对ARDS的临床救治具有重要意义。 |
| 关键词: 肺保护性通气 急性呼吸窘迫综合征 临床疗效 |
| DOI：10.3969/j.issn.1674-3806.2015.09.14 |
| 分类号:R 563.8 |
| 基金项目: |
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| The effect of lung protective ventilation strategies on acute respiratory distress syndrome |
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ZHONG Hua-qiang, HUANG Ke-zan
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Department of Emergency, the People ′s Hospital of Binyang County, Guangxi 530400, China
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| Abstract: |
| ［Abstract］ Objective To evaluate the clinical effect of lung protective ventilation strategies on acute respiratory distress syndrome(ARDS).Methods 62 patients with acute respiratory distress syndrome were randomly divided into the control group(n=30) and the observation group(n=32). The control group was treated with conventional ventilation strategy, and the observation group was treated with lung protective ventilation strategies.PaO2, PaCO2, PaCO2/FiO2 and ventilation time, hospitalization days and the rate of ventilator associated lung injury(VALI) were compared between the two groups.Results PaO2, PaCO2 and PaO2/FiO2 at 8 h, 24 h and 48 h after ventilation in the observation were signigicantly higher than those in the control group(P<0.05). The ventilation time, hospitalization days and the rate of VALI in the observation group were signigicantly shorter or lower than those in the control group(P<0.05).Conclusion Using lung protective ventilation strategies for acute respiratory distress syndrome can signigicantly shorten the ventilation time, hospitalization days and reduce the incidence of VALI. It has important clinical significance for ARDS. |
| Key words: Lung protective ventilation strategies Acute respiratory distress syndrome（ARDS） Clinical effect |
