| 摘要: |
| ［摘要］ 目的 探讨妊娠期孕妇糖代谢异常对外阴阴道假丝酵母菌感染及妊娠结局的影响。方法 收集行产前检查并足月分娩的初次孕产妇1 056例，根据葡萄糖筛查试验（GCT）结果将孕妇分为血糖正常组624例，GCT异常组326例，妊娠期糖尿病（GDM)组106例。观察三组在妊娠期间外阴阴道假丝酵母菌病(VVC)的发生情况及妊娠结局情况。结果 GDM组、GCT异常组VVC发生率差异无统计学意义(P>0.05)，但均明显高于血糖正常组(P<0.05)；三组VVC复发率差异无统计学意义(P>0.05)。GCT异常组、GDM组的胎膜早破、胎儿宫内窘迫发生率、剖宫产率、足月低体重儿率明显高于血糖正常组（P<0.01）；且GDM组又高于GCT异常组（P<0.01）。结论 妊娠期孕妇糖代谢异常会增加VVC发生的风险，增加剖宫产、胎膜早破、胎儿宫内窘迫的风险，应加以重视。 |
| 关键词: 妊娠期糖尿病 糖代谢异常 外阴阴道假丝酵母菌 妊娠结局 |
| DOI：10.3969/j.issn.1674-3806.2015.11.18 |
| 分类号:R 714.256 |
| 基金项目: |
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| The influence of gestational abnormal glucose metabolism on vulvovaginal candidiasis infection and pregnancy outcome |
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DONG Hai-ling
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Department of Obstetrics and Gynecology, the People′s Hospital of Shouguang City, Shandong 262700, China
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| Abstract: |
| ［Abstract］ Objective To investigate the effect of abnormal glucose metabolism on vulvovaginal candidiasis infection and pregnancy outcome in pregnant women.Methods One thousand and fifty-six pregnant women were collected who did prenatal examination and termly deliveried in the department of obstetrics and gynecology of our hospital from Jun 2011 to Jun 2013. According to the glucose screening test results, they were divided into glucose normal group（n=624）, GCT abnormal group（n=326）and gestational diabetes mellitus(GDM) group(n=106). The occurrence of the vulvovaginal candidiasis(VVC) infection and pregnancy outcome of the three groups were observed during pregnancy.Results The occurrence rates of VVC of GCT abnormal group and GDM group had no significant differences(P>0.05), but they were significantly higher than those of glucose normal group(P<0.05). The recurrence rate of VVC among the three group had no significant difference(P>0.05).Conclusion Abnormal glucose metabolism during pregnancy may increase occurrence risk of VVC, which affects the outcome of pregnancy and increases the risk of cesarean section and premature rupture of membranes and intrauterine fetal distress, thus it should be payed more attention to the changes of blood glucose level. Glycated hemoglobin level in pregnant women should be monitored. |
| Key words: Gestational diabetes mellitus Abnormal glucose metabolism Vulvovaginal candidiasis Pregnancy outcome |
